Evidence map›Paper›PMID 22381023›Full record

ArticleThe Journal of pediatrics2012

Physical comorbidity of migraine and other headaches in US adolescents.

Tarannum M Lateef, Lihong Cui, Karin B Nelson, Erin F Nakamura, Kathleen R Merikangas

Abstract read
In one paragraph

Article in The Journal of pediatrics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Headache in school children: prevalence and risk factors.Deutsches Arzteblatt international · 2013
    Pooled it
  3. Article
  4. Article
  5. Migraine, Allergy, and Histamine: Is There a Link?Journal of clinical medicine · 2023
    Review
  6. Recurrent Epistaxis: An Unusual Manifestation of Clinical Spectrum of Migraine -Case Series with Scoping Review of Literature.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023
    Article
  7. Article
  8. Article
  9. Review
  10. Pathophysiological Bases of Comorbidity in Migraine.Frontiers in human neuroscience · 2021
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Effect of Vitamin D supplementation on symptoms and C-reactive protein in migraine patients.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2015
    Article
  16. Article
  17. Headache and epilepsy.Current pain and headache reports · 2013
    Review
  18. Article
  19. Review
  20. The relationship between serum levels of vitamin D and migraine.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Tarannum M LateefGenetic Epidemiology Research Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA. TLateef@cnmc.org
Lihong Cui
Karin B Nelson
Erin F Nakamura
Kathleen R Merikangas
Children's National · USNational Institute of Mental Health · USNational Institutes of Health · US

Funding

EPIDEMIOLOGY-- NATIONAL COMORBIDITY SURVEY REPLICATIONU01MH060220 · NIMH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI KESSLER, RONALD C · 1999 to 2010
$18.7M
National Comorbidity Survey - Adolescent (NCS-A)ZIAMH002808 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI MERIKANGAS, KATHLEEN R · 2009 to 2015
$3.2M
National Comorbidity Survey - Adolescent (NCS-A)Z01MH002808 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI MERIKANGAS, KATHLEEN R · 2003 to 2008
$316k
Intramural NIH HHS Z01 MH002808Intramural NIH HHS ZIA MH002808NIMH NIH HHS U01 MH060220NIMH NIH HHS U01-MH60220NIMH NIH HHS Z01 MH002808-08
6 · The paper itself

Abstract

objectiveTo examine the pattern and extent to which other physical conditions are comorbid with migraine and other headaches in youth in a representative sample of the US population. STUDY

designThe National Comorbidity Survey-Adolescent Supplement is a face-to-face survey of adolescents aged 13-18 years in the continental US. Sufficient information to assess the International Headache Society's criteria for migraine with and without aura over the past 12 months was available in the diagnostic module. A caretaker/parental self-administered report was used to assess a broad range of other physical conditions. The sample for these analyses was 6843 adolescents with systematic caretaker/parent reports.

resultsAdolescents with any headaches reported higher rates of other neurologic conditions, including epilepsy (OR, 2.02; 95% CI, 1.04-3.94), persistent nightmares (OR, 2.28; 95% CI, 1.34-3.87), and motion sickness (OR, 1.6; 95% CI, 1.07-2.4), as well as abdominal complaints (OR, 2.36; 95% CI, 1.59-3.51). Asthma (OR, 2.22; 95% CI, 1.26-3.92) and seasonal allergies (OR, 1.66; 95% CI, 1.12-2.48) were more common in adolescents with migraines than in adolescents with nonspecific headaches.

conclusionAdolescent migraine is associated with inflammatory conditions such as asthma and seasonal allergies, as well as with epilepsy, persistent nightmares, and motion sickness. Our findings suggest that comorbid medical conditions should be evaluated comprehensively in determining treatment options in youth with headache. Such comorbidity also could be an important source of the clinical and etiologic heterogeneity in migraine.

Indexed as

AdolescentComorbidityFemaleHeadacheHumansMaleMigraine DisordersSurveys and QuestionnairesUnited States

Identifiers

PMID22381023
PMCPMC4408276
OpenAlexW2035473688

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.