ArticleSexually transmitted infections2012
Multilevel and spatial analysis of syphilis in Shenzhen, China, to inform spatially targeted control measures.
Article in Sexually transmitted infections, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 22 citations in OpenAlex.
- Distribution of reported syphilis cases in South China: spatiotemporal analysis.Scientific reports · 2018Trial
- Preconception syphilis seroprevalence and association with duration of marriage and age among married individuals in Guangdong Province, China: A population-based cross-sectional study.PLoS neglected tropical diseases · 2022Article
- Spatial Heterogeneity and Its Influencing Factors of Syphilis in Ningxia, Northwest China, from 2004 to 2017: A Spatial Analysis.International journal of environmental research and public health · 2022Article
- Couple-level determinants of syphilis infection among heterosexual married couples of reproductive age in Guangdong Province, China: A population-based cross-sectional study.Frontiers in public health · 2022Article
- Spatiotemporal distribution and sociodemographic and socioeconomic factors associated with primary and secondary syphilis in Guangdong, China, 2005-2017.PLoS neglected tropical diseases · 2021Article
- Predictors of serological cure after penicillin therapy in HIV-negative patients with early syphilis in Shenzhen, China.PloS one · 2021Article
- The association between human perceived heat and early-stage syphilis and its variance: Results from a case-report system.The Science of the total environment · 2017Article
- Stages of syphilis in South China - a multilevel analysis of early diagnosis.BMC public health · 2017Article
- The current status of syphilis prevention and control in Jiangsu province, China: A cross-sectional study.PloS one · 2017Article
- Spatial distribution and cluster analysis of risky sexual behaviours and STDs reported by Chinese adults in Guangzhou, China: a representative population-based study.Sexually transmitted infections · 2016Article
- Influence of Detection Method and Study Area Scale on Syphilis Cluster Identification in North Carolina.Sexually transmitted diseases · 2016Article
- Poor awareness of syphilis prevention and treatment knowledge among six different populations in south China.BMC public health · 2016Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 2 countries.
Funding
Abstract
objectivesThe present study investigates the varied spatial distribution of syphilis cases in Shenzhen, China, and explores the individual-, neighbourhood- and district-level factors affecting the distribution.
methodsThis study uses spatial analysis and multi-level generalised estimating equations to explore the spatial distribution of reported syphilis cases among individuals in Shenzhen, Guangdong Province, China. The spatial distribution of primary/secondary and latent cases was investigated using the Moran's I-statistic. Primary/secondary syphilis cases were compared with all syphilis cases using a three-level model with individual (n=6496), neighbourhood (n=55) and district (n=6) levels.
resultsA total of 6496 syphilis cases were reported in 2009 with 35.8% primary and secondary syphilis cases. Both primary/secondary syphilis cases (Moran's I value=0.33, p<0.01) and latent syphilis cases (Moran's I value=0.19, p<0.01) showed significant spatial clustering at the neighbourhood level. Adjusting for the number of reporting hospitals, the best model found that the following characteristics were associated with primary/secondary syphilis infection: individuals who are younger in age (p=0.003), male (p<0.001), migrant labourers (p=0.047) and those who live in districts with a higher gross domestic product (p<0.001).
conclusionsThere is substantial clustering of primary and secondary syphilis cases at the neighbourhood level in Shenzhen, suggesting the need for greater STD health service provision in these clustered neighbourhoods. Spatially targeted syphilis control measures may be useful to optimise testing, treatment and partner services.
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