ArticleJournal of clinical microbiology2012
Ultrarapid detection of blaKPC₁/₂-₁₂ from perirectal and nasal swabs by use of real-time PCR.
Article in Journal of clinical microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Improved blood culture workflow for faster identification of KPC-producing Enterobacterales.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2019Article
- Intestinal Carriage of Carbapenemase-Producing Organisms: Current Status of Surveillance Methods.Clinical microbiology reviews · 2016Review
- Clinical Performance of Check-Direct CPE, a Multiplex PCR for Direct Detection of bla(KPC), bla(NDM) and/or bla(VIM), and bla(OXA)-48 from Perirectal Swabs.Journal of clinical microbiology · 2015Article
- Comparison of phenotypic methods for the detection of carbapenem non-susceptible Enterobacteriaceae.Gut pathogens · 2014Article
- Rapid and direct real-time detection of blaKPC and blaNDM from surveillance samples.Journal of clinical microbiology · 2013Article
- Detection of colonization by carbapenemase-producing Gram-negative Bacilli in patients by use of the Xpert MDRO assay.Journal of clinical microbiology · 2013Article
- The establishment of a duplex real-time PCR assay for rapid and simultaneous detection of blaNDM and blaKPC genes in bacteria.Annals of clinical microbiology and antimicrobials · 2013Article
- A combined disk test for direct differentiation of carbapenemase-producing enterobacteriaceae in surveillance rectal swabs.Journal of clinical microbiology · 2013Article
- Rapid and simultaneous detection of genes encoding Klebsiella pneumoniae carbapenemase (blaKPC) and New Delhi metallo-β-lactamase (blaNDM) in Gram-negative bacilli.Journal of clinical microbiology · 2013Article
- Antimicrobial treatment and containment measures for an extremely drug-resistant Klebsiella pneumoniae ST101 isolate carrying pKPN101-IT, a novel fully sequenced bla(KPC-2) plasmid.Journal of clinical microbiology · 2012Article
- Multiplex real-time PCR for detection of an epidemic KPC-producing Klebsiella pneumoniae ST258 clone.Antimicrobial agents and chemotherapy · 2012Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The novel real-time PCR assay developed as described here was able to detect bla(KPC1/2-12) (bla(KPC-1/2) to bla(KPC-12)) from easily available clinical specimens in less than 2 h. The genotypic assay was highly sensitive (100%) and specific (98%). In some cases, it was able to detect bla(KPC) 48 h before positive detection by standard phenotypic assay on patients who were monitored daily. The high sensitivity and rapidity of the molecular method make it the method of choice for KPC surveillance and, thus, containment purposes.
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