ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2012
Neurons with stereotyped and rapid responses provide a reference frame for relative temporal coding in primate auditory cortex.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 48 citations in OpenAlex.
- Distinct neuronal types contribute to hybrid temporal encoding strategies in primate auditory cortex.PLoS biology · 2022Article
- Neural readout of a latency code in the active electrosensory system.Cell reports · 2022Article
- Local prothoracic auditory neurons in Ensifera.Frontiers in neuroscience · 2022Article
- PV+ Cells Enhance Temporal Population Codes but not Stimulus-Related Timing in Auditory Cortex.Cerebral cortex (New York, N.Y. : 1991) · 2019Article
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- Gain Control in the Auditory Cortex Evoked by Changing Temporal Correlation of Sounds.Cerebral cortex (New York, N.Y. : 1991) · 2017Article
- Stable encoding of sounds over a broad range of statistical parameters in the auditory cortex.The European journal of neuroscience · 2016Article
- A Readout Mechanism for Latency Codes.Frontiers in computational neuroscience · 2016Article
- Packet-based communication in the cortex.Nature reviews. Neuroscience · 2015Review
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- Neurons and networks organizing and sequencing memories.Brain research · 2015Article
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- Diverse cortical codes for scene segmentation in primate auditory cortex.Journal of neurophysiology · 2015Article
- Neural population coding: combining insights from microscopic and mass signals.Trends in cognitive sciences · 2015Review
- Reading spike timing without a clock: intrinsic decoding of spike trains.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2014Review
- Speech sound processing deficits and training-induced neural plasticity in rats with dyslexia gene knockdown.PloS one · 2014Article
- Encoding of ultrasonic vocalizations in the auditory cortex.Journal of neurophysiology · 2013Article
- Neural variability, or lack thereof.Frontiers in computational neuroscience · 2013Article
- Comparison of latency and rate coding for the direction of whisker deflection in the subcortical somatosensory pathway.Journal of neurophysiology · 2012Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The precise timing of spikes of cortical neurons relative to stimulus onset carries substantial sensory information. To access this information the sensory systems would need to maintain an internal temporal reference that reflects the precise stimulus timing. Whether and how sensory systems implement such reference frames to decode time-dependent responses, however, remains debated. Studying the encoding of naturalistic sounds in primate (Macaca mulatta) auditory cortex we here investigate potential intrinsic references for decoding temporally precise information. Within the population of recorded neurons, we found one subset responding with stereotyped fast latencies that varied little across trials or stimuli, while the remaining neurons had stimulus-modulated responses with longer and variable latencies. Computational analysis demonstrated that the neurons with stereotyped short latencies constitute an effective temporal reference for relative coding. Using the response onset of a simultaneously recorded stereotyped neuron allowed decoding most of the stimulus information carried by onset latencies and the full spike train of stimulus-modulated neurons. Computational modeling showed that few tens of such stereotyped reference neurons suffice to recover nearly all information that would be available when decoding the same responses relative to the actual stimulus onset. These findings reveal an explicit neural signature of an intrinsic reference for decoding temporal response patterns in the auditory cortex of alert animals. Furthermore, they highlight a role for apparently unselective neurons as an early saliency signal that provides a temporal reference for extracting stimulus information from other neurons.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.