Evidence map›Paper›PMID 22378593›Full record

ReviewNeurourology and urodynamics2012

Do the urinary bladder and large bowel interact, in sickness or in health? ICI-RS 2011.

Anna P Malykhina, Jean-Jacques Wyndaele, Karl-Erik Andersson, Stefan De Wachter, Roger R Dmochowski

Abstract readReview
In one paragraph

Review in Neurourology and urodynamics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Detecting Multimorbidity Patterns with Association Rule Mining in Patients with Alzheimer's Disease and Related Dementias.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2024
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Acyloxyacyl hydrolase is a host determinant of gut microbiome-mediated pelvic pain.American journal of physiology. Regulatory, integrative and comparative physiology · 2021
    Article
  15. Article
  16. Review
  17. Article
  18. Acyloxyacyl hydrolase modulates pelvic pain severity.American journal of physiology. Regulatory, integrative and comparative physiology · 2018
    Article
  19. Voltage-gated sodium channels: (NaThe Journal of physiology · 2018
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anna P MalykhinaDepartment of Surgery, University of Pennsylvania, Glenolden, Pennsylvania 19036-2307, USA. anna.malykhina@uphs.upenn.edu
Jean-Jacques Wyndaele
Karl-Erik Andersson
Stefan De Wachter
Roger R Dmochowski

Funding

Cross-sensitization in the pelvis and neurogenic bladderR01DK077699 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI MALYKHINA, ANNA P · 2008 to 2012
$1.9M
NIDDK NIH HHS DK077699NIDDK NIH HHS DK 077699-S2NIDDK NIH HHS R01 DK077699
6 · The paper itself

Abstract

Normal functioning of the urinary bladder and the distal gut is an essential part of daily physiological activity coordinated by the peripheral and central nervous systems. Pathological changes in one of these organs may induce the development of cross-organ sensitization in the pelvis and underlie clinical co-morbidity of genitourinary and GI dysfunctions. Experimental human and animal data suggest that the bladder and distal colon interact under both normal and pathological conditions, however, the directions of these interactions can change dramatically depending on the nature and duration of the applied stimuli. This review article aimed to summarize the clinical data on colon-bladder cross-reflexes in healthy individuals, as well as in patients with co-morbid disorders. It also discusses currently used animal models, experimental approaches, and suggested mechanisms of colon-bladder cross-talk. Additionally, it provides an overview of the potential pharmacological targets to develop treatment options for patients with co-morbid disorders. Presented work resulted from the discussion of colon/bladder interactions during "Think Tank 9" presentations at the International Consultation on Incontinence Research Society meeting held in Bristol, UK, 2011.

Indexed as

AnimalsColonColonic DiseasesComorbidityDisease Models, AnimalEvidence-Based MedicineHumansReflexUrinary BladderUrinary Bladder Diseases

Identifiers

PMID22378593
PMCPMC3309116

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.