Evidence map›Paper›PMID 22378422›Full record

ArticleOptics letters2012

Dual-modality photothermal optical coherence tomography and magnetic-resonance imaging of carbon nanotubes.

Jason M Tucker-Schwartz, Tu Hong, Daniel C Colvin, Yaqiong Xu, Melissa C Skala

Abstract read
In one paragraph

Article in Optics letters, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jason M Tucker-SchwartzDepartment of Biomedical Engineering, Vanderbilt University, VU Station B Box 351631, Nashville, Tennessee 37235, USA.
Tu Hong
Daniel C Colvin
Yaqiong Xu
Melissa C Skala
Vanderbilt University · US

Funding

Functional Optical Coherence Tomography for Monitoring Drug Resistance in CancerR00CA142888 · NCI · VANDERBILT UNIVERSITY · PI SKALA, MELISSA CAROLINE · 2010 to 2012
$727k
NCI NIH HHS R00 CA142888
6 · The paper itself

Abstract

We demonstrate polyethylene-glycol-coated single-walled carbon nanotubes (CNTs) as contrast agents for both photothermal optical coherence tomography (OCT) and magnetic-resonance imaging (MRI). Photothermal OCT was accomplished with a spectral domain OCT system with an amplitude-modulated 750 nm pump beam using 10 mW of power, and T(2) MRI was achieved with a 4.7 T animal system. Photothermal OCT and T(2) MRI achieved sensitivities of nanomolar concentrations to CNTs dispersed in amine-terminated polyethylene glycol, thus establishing the potential for dual-modality molecular imaging with CNTs.

Indexed as

Imaging, Three-DimensionalMagnetic Resonance ImagingNanotubes, CarbonPhantoms, ImagingTemperatureTomography, Optical CoherenceNanotubes, Carbon

Identifiers

PMID22378422
PMCPMC3390748
OpenAlexW2039072263

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.