Evidence map›Paper›PMID 22377389›Full record

Trial reportJournal of substance abuse treatment2012

Project Impact: a pharmacotherapy pilot trial investigating the abstinence and treatment adherence of Latino light smokers.

Marcel A de Dios, Bradley J Anderson, Cassandra Stanton, Daniel A Audet, Michael Stein

Abstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of substance abuse treatment, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 8 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 8 syntheses or guidelines pooled it, 48 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Nicotine receptor partial agonists for smoking cessation.The Cochrane database of systematic reviews · 2023
    Pooled it
  7. Nicotine receptor partial agonists for smoking cessation.The Cochrane database of systematic reviews · 2016
    Pooled it
  8. Sex Differences in Varenicline Efficacy for Smoking Cessation: A Meta-Analysis.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2016
    Pooled it
  9. Trial
  10. Trial
  11. Varenicline for Smoking Cessation in Light Smokers.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2016
    Trial
  12. Trial
  13. Outcomes of a Tailored Intervention for Cigarette Smoking Cessation Among Latinos Living With HIV/AIDS.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2015
    Trial
  14. A double-blind placebo-controlled randomized trial of varenicline for smokeless tobacco dependence in India.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2014
    Trial
  15. Trial
  16. Article
  17. Article
  18. Article
  19. Article
  20. Adherence to Pharmacological Smoking Cessation Interventions: A Literature Review and Synthesis of Correlates and Barriers.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Marcel A de DiosDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI 02912, USA. mdedios@butler.org
Bradley J Anderson
Cassandra Stanton
Daniel A Audet
Michael Stein
Butler Hospital · USBrown University · USProvidence College · US

Funding

Varenicline versus Nicotine Replacement for Methadone-Maintained SmokersR01CA129226 · NCI · BUTLER HOSPITAL (PROVIDENCE, RI) · PI STEIN, MICHAEL D · 2008 to 2012
$2.6M
MOTIVATION AND PATCH TREATMENT FOR HIV POSITIVE SMOKERSR01DA012344 · NIDA · MIRIAM HOSPITAL · PI LLOYD-RICHARDSON, ELIZABETH E · 1999 to 2003
$2.0M
MIDCAREER INVESTIGATOR AWARD IN SUBSTANCE ABUSE RESEARCHK24DA000512 · NIDA · RHODE ISLAND HOSPITAL (PROVIDENCE, RI) · PI STEIN, MICHAEL D · 2001 to 2010
$982k
Peer Group Networks and Adolescent SmokingK07CA095623 · NCI · MIRIAM HOSPITAL · PI STANTON, CASSANDRA A · 2004 to 2008
$635k
NCI NIH HHS K07 CA095623NCI NIH HHS K07-CA95623NCI NIH HHS R01CA0129226-S1NCI NIH HHS R01 CA129226NIDA NIH HHS K24 DA000512NIDA NIH HHS K24-DA000512NIDA NIH HHS R01 DA012344NIDA NIH HHS R01-DA12344NIMHD NIH HHS L60 MD002915
6 · The paper itself

Abstract

Light smoking is particularly prevalent among Latino smokers. Nicotine replacement (NRT) and varenicline are effective medications for smoking cessation for moderate-heavy smokers but have not been tested in light smokers, and thus, there are no treatment guidelines for use with light smokers. This pilot trial tested the efficacy of NRT and varenicline in increasing smoking abstinence among Latino light smokers. A 3-group (NRT, varenicline, and varenicline-placebo) randomized design was used, and Latino light smokers (≤10 cigarettes per day) received 12 weeks of treatment, which included a culturally informed behavioral health session and ongoing medication management visits. At follow-up, there were no abstinent participants in the placebo and NRT groups. However, 30% of participants in the varenicline group were abstinent at the 3-, 4-, and 6-month follow-up. This study represents the only investigation that specifically targets Latino light smokers using these treatments and characterizing their treatment adherence.

Indexed as

Tobacco Use Cessation DevicesAdultBehavior TherapyBenzazepinesCombined Modality TherapyDouble-Blind MethodFemaleFollow-Up StudiesHispanic or LatinoHumansMaleMedication AdherenceMiddle AgedNicotinic AgonistsPilot ProjectsQuinoxalinesBenzazepinesNicotinic AgonistsQuinoxalinesVarenicline

Identifiers

PMID22377389
PMCPMC3762477
OpenAlexW2003016875

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.