ArticleClinical and translational science2012
Developing robust, sustainable, implementation systems using rigorous, rapid and relevant science.
Article in Clinical and translational science, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 170 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
170 citing papers in PubMed, 5 syntheses or guidelines pooled it, 281 citations in OpenAlex.
- Effectiveness and Implementation of Digital Health Interventions on Physiological, Psychological, and Functional Outcomes in Adults With Multimorbidity: Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of medical Internet research · 2026Pooled it
- Investigating the implementation of infection prevention and control practices in neonatal care across country income levels: a systematic review.Antimicrobial resistance and infection control · 2025Pooled it
- Efficacy of sustained knowledge translation (KT) interventions in chronic disease management in older adults: systematic review and meta-analysis of complex interventions.BMC medicine · 2023Pooled it
- Assessing trauma care systems in low-income and middle-income countries: a systematic review and evidence synthesis mapping the Three Delays framework to injury health system assessments.BMJ global health · 2021Pooled it
- Pooled it
- Using After Action Review to Identify Rapid Response Implementation Strategies for Emerging Drugs Among Youth.Prevention science : the official journal of the Society for Prevention Research · 2025Trial
- Development and application of a qualitative rapid analysis framework in a hybrid trial within primary care.BMJ open · 2024Trial
- Translation of a family-based behavioral intervention for adolescent obesity using the RE-AIM framework and common steps from adaptation frameworks.Translational behavioral medicine · 2023Trial
- Sustainability of Evidence-Based Acute Pain Management Practices for Hospitalized Older Adults.Western journal of nursing research · 2018Trial
- Integrated solutions for sustainable fall prevention in primary care, the iSOLVE project: a type 2 hybrid effectiveness-implementation design.Implementation science : IS · 2017Trial
- An effectiveness-implementation hybrid trial study protocol targeting posttraumatic stress disorder and comorbidity.Implementation science : IS · 2016Trial
- Role of Context, Resources, and Target Population in the Fidelity of Critical Time Intervention.Psychiatric services (Washington, D.C.) · 2016Trial
- Community-based implementation and effectiveness in a randomized trial of a risk reduction intervention for HIV-serodiscordant couples: study protocol.Implementation science : IS · 2014Trial
- Randomized Effectiveness Trial of the New Beginnings Program for Divorced Families with Children and Adolescents.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53Trial
- The development and implementation of a brief intervention for medically admitted suicide attempt survivors.General hospital psychiatryTrial
- Improving science will require more than just training.Clinical psychological science : a journal of the Association for Psychological Science · 2026Article
- Strengthening awareness and community resources for early detection of lung cancer through navigation guided screening in American Indian/Alaska Native clinics (SACRED LUNGS): Study protocol.Contemporary clinical trials · 2026Article
- When to Halt Implementation: Barriers in a Lay Counselor Narrative Exposure Therapy Training Program.Community mental health journal · 2026Article
- Tracing the threads: a system dynamics and network diffusion model of kangaroo care implementation in neonatal care.Implementation science communications · 2026Article
- Reciprocal innovation in implementation science and global health: reflections from the EXTRA-CVD (extending the HIV treatment cascade for cardiovascular disease prevention) study.BMC global and public health · 2026Review
110 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCurrent approaches to medical science generally have not resulted in rapid, robust integration into feasible, sustainable real world healthcare programs and policies. Implementation science risks falling short of expectations if it aligns with historical norms. Fundamentally different scientific approaches are needed to accelerate such integration.
methodsWe propose that the key goal of implementation science should be to study the development, spread and sustainability of broadly applicable and practical programs, treatments, guidelines, and policies that are contextually relevant and robust across diverse settings, delivery staff, and subgroups. We recommend key conceptual and methodological characteristics needed to accomplish these goals.
resultsThe methods to produce such advances should be rapid, rigorous, transparent, and contextually relevant. We recommend approaches that incorporate a systems perspective, investigate generalizability, are transparent, and employ practical measures and participatory approaches.
conclusionsTo produce different outcomes, we need to think and act differently. Implications of such an implementation science approach include fundamental changes that should be relevant to Clinical Translational Science Award investigators, comparative effectiveness researchers, those interested in pragmatic trials, grant funders, and community partners.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.