Evidence map›Paper›PMID 22374871›Full record

ArticleAmerican journal of hematology2012

miR-199b-5p directly targets PODXL and DDR1 and decreased levels of miR-199b-5p correlate with elevated expressions of PODXL and DDR1 in acute myeloid leukemia.

Amanda J Favreau, Erin L Cross, Pradeep Sathyanarayana

Abstract readLetter
In one paragraph

Article in American journal of hematology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 55 citations in OpenAlex.

  1. Article
  2. [MiR-6838-5p overexpression inhibits proliferation of breast cancer MCF-7 cells by downregulating DDR1 expression].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024
    Article
  3. Article
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  9. Review
  10. MicroRNA-486-3p functions as a tumor suppressor in oral cancer by targeting DDR1.Journal of experimental & clinical cancer research : CR · 2019
    Article
  11. Article
  12. PODXL, negatively regulated by KLF4, promotes the EMT and metastasis and serves as a novel prognostic indicator of gastric cancer.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2019
    Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Amanda J Favreau
Erin L Cross
Pradeep Sathyanarayana
Maine Medical Center Research Institute · US

Funding

WNT SIGNALING IN PREIMPLANTATION EMBRYOP20RR018789 · NCRR · MAINE MEDICAL CENTER · PI WOJCHOWSKI, DON MICHAEL · 2003 to 2011
$18.9M
Phase III COBRE in Vascular BiologyP30GM103392 · NIGMS · MAINEHEALTH · PI ST. GERMAIN, DONALD L. · 2012 to 2016
$4.7M
COBRE in Stem Cell Biology and Regenerative MedicineP20GM103465 · NIGMS · MAINEHEALTH · PI WOJCHOWSKI, DON MICHAEL · 2012 to 2012
$2.0M
PHASE III COBRE IN VASCULAR BIOLOGYP30RR030927 · NCRR · MAINEHEALTH · PI FRIESEL, ROBERT E · 2011 to 2011
$1.2M
NCRR NIH HHS P20 RR018789NCRR NIH HHS P30 RR030927NIGMS NIH HHS P20 GM103465NIGMS NIH HHS P30 GM103392
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

3' Untranslated RegionsBone MarrowCollagen Type IVDiscoidin Domain Receptor 1Gene Expression Regulation, LeukemicGene SilencingGenetic VectorsHumansK562 CellsLeukemia, Myeloid, AcuteLeukemia, Myelomonocytic, AcuteMicroRNAsMolecular Targeted TherapyNeoplasm ProteinsReceptor Protein-Tyrosine KinasesSialoglycoproteins3' Untranslated RegionsCollagen Type IVDDR1 protein, humanDiscoidin Domain Receptor 1MicroRNAsmirn199 microRNA, humanNeoplasm ProteinspodocalyxinReceptor Protein-Tyrosine KinasesSialoglycoproteins

Identifiers

PMID22374871
PMCPMC4104571
OpenAlexW2003821826

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.