ReviewNeuroscience and biobehavioral reviews2012
A neuroanatomical model of prefrontal inhibitory modulation of memory retrieval.
Review in Neuroscience and biobehavioral reviews, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
47 citing papers in PubMed, 1 synthesis or guideline pooled it.
- How acute total sleep loss affects the attending brain: a meta-analysis of neuroimaging studies.Sleep · 2015Pooled it
- Prefrontally driven downregulation of neural synchrony mediates goal-directed forgetting.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Trial
- Review
- Functional connectivity patterns in preschool children associated with working memory performance and digital device use.Scientific reports · 2025Article
- Associative coding of conditioned fear in the thalamic nucleus reuniens in rodents and humans.Communications biology · 2025Article
- Brain mechanisms underlying the inhibitory control of thought.Nature reviews. Neuroscience · 2025Review
- Inhibitory control in addictive behaviors: is there room for memory suppression?Frontiers in human neuroscience · 2025Article
- Reduced hippocampal-cortical connectivity during memory suppression predicts the ability to forget unwanted memories.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Article
- Partially overlapping spatial environments trigger reinstatement in hippocampus and schema representations in prefrontal cortex.Nature communications · 2021Article
- The Mechanisms Underlying Interference and Inhibition: A Review of Current Behavioral and Neuroimaging Research.Brain sciences · 2021Review
- Dimensions and mechanisms of memory organization.Neuron · 2021Review
- Varying demands for cognitive control reveals shared neural processes supporting semantic and episodic memory retrieval.Nature communications · 2021Observational
- Binge drinking is associated with altered resting state functional connectivity of reward-salience and top down control networks.Brain imaging and behavior · 2020Article
- The medial prefrontal cortex is needed for resolving interference even when there are no changes in task rules and strategies.Behavioral neuroscience · 2020Article
- Neuroscience of Adolescent Anorexia Nervosa: Implications for Family-Based Treatment (FBT).Frontiers in psychiatry · 2020Article
- Dorsomedial prefrontal cortex neurons encode nicotine-cue associations.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2019Article
- Disrupting the medial prefrontal cortex alters hippocampal sequences during deliberative decision making.Journal of neurophysiology · 2019Article
- The Predictive Processing Model of EMDR.Frontiers in psychology · 2019Article
- Ventral Midline Thalamus Is Necessary for Hippocampal Place Field Stability and Cell Firing Modulation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
Corrections and comments
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Authors and funding
1 author.
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Abstract
Memory of past experience is essential for guiding goal-related behavior. Being able to control accessibility of memory through modulation of retrieval enables humans to flexibly adapt to their environment. Understanding the specific neural pathways of how this control is achieved has largely eluded cognitive neuroscience. Accordingly, in the current paper I review literature that examines the overt control over retrieval in order to reduce accessibility. I first introduce three hypotheses of inhibition of retrieval. These hypotheses involve: (i) attending to other stimuli as a form of diversionary attention, (ii) inhibiting the specific individual neural representation of the memory, and (iii) inhibiting the hippocampus and retrieval process more generally to prevent reactivation of the representation. I then analyze literature taken from the White Bear Suppression, Directed Forgetting and Think/No-Think tasks to provide evidence for these hypotheses. Finally, a neuroanatomical model is developed to indicate three pathways from PFC to the hippocampal complex that support inhibition of memory retrieval. Describing these neural pathways increases our understanding of control over memory in general.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.