ArticleProceedings of the National Academy of Sciences of the United States of America2012
Induced mutations in circadian clock regulator Mat-a facilitated short-season adaptation and range extension in cultivated barley.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
85 citing papers in PubMed, 175 citations in OpenAlex.
- Elucidation of the genetic architecture stabilizing the heading time in barley (Hordeum vulgare L.).Planta · 2026Article
- From photoperiod thresholds to photoperiod sensitivity: dual strategies for cost-effective speed breeding and climate-ready barley.Frontiers in plant science · 2026Article
- Transcriptional activation and repression in the plant circadian clock: Revisiting core oscillator feedback loops and output pathways.Plant communications · 2025Review
- Translational insights into abiotic interactions: From Arabidopsis to crop plants.The Plant cell · 2025Review
- Phosphorus-Mediated Transition from Vegetative to Reproductive Growth in Dwarf Coconut (International journal of molecular sciences · 2024Article
- Tracing the Evolutionary History of the Temperature-Sensing Prion-like Domain in EARLY FLOWERING 3 Highlights the Uniqueness of AtELF3.Molecular biology and evolution · 2024Article
- Genetic mapping reveals new loci and alleles for flowering time and plant height using the double round-robin population of barley.Journal of experimental botany · 2024Article
- A guide to barley mutants.Hereditas · 2024Review
- Dynamic Phytomeric Growth Contributes to Local Adaptation in Barley.Molecular biology and evolution · 2024Article
- early maturity 7 promotes early flowering by controlling the light input into the circadian clock in barley.Plant physiology · 2024Article
- Novel exotic alleles of EARLY FLOWERING 3 determine plant development in barley.Journal of experimental botany · 2023Article
- EARLY FLOWERING 3 interactions with PHYTOCHROME B and PHOTOPERIOD1 are critical for the photoperiodic regulation of wheat heading time.PLoS genetics · 2023Article
- PHYTOCHROME C regulation of photoperiodic flowering via PHOTOPERIOD1 is mediated by EARLY FLOWERING 3 in Brachypodium distachyon.PLoS genetics · 2023Article
- Wheat EARLY FLOWERING 3 affects heading date without disrupting circadian oscillations.Plant physiology · 2023Article
- The evening complex promotes maize flowering and adaptation to temperate regions.The Plant cell · 2023Article
- Identification of a candidate dwarfing gene in Pallas, the first commercial barley cultivar generated through mutational breeding.Frontiers in genetics · 2023Article
- Altered regulation of flowering expands growth ranges and maximizes yields in major crops.Frontiers in plant science · 2023Review
- Plant clock modifications for adapting flowering time to local environments.Plant physiology · 2022Article
- The evening complex integrates photoperiod signals to control flowering in rice.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Experimental Verification of Inferred Regulatory Interactions ofmicroPublication biology · 2022Article
25 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Time to flowering has an important impact on yield and has been a key trait in the domestication of crop plants and the spread of agriculture. In 1961, the cultivar Mari (mat-a.8) was the very first induced early barley (Hordeum vulgare L.) mutant to be released into commercial production. Mari extended the range of two-row spring barley cultivation as a result of its photoperiod insensitivity. Since its release, Mari or its derivatives have been used extensively across the world to facilitate short-season adaptation and further geographic range extension. By exploiting an extended historical collection of early-flowering mutants of barley, we identified Praematurum-a (Mat-a), the gene responsible for this key adaptive phenotype, as a homolog of the Arabidopsis thaliana circadian clock regulator Early Flowering 3 (Elf3). We characterized 87 induced mat-a mutant lines and identified >20 different mat-a alleles that had clear mutations leading to a defective putative ELF3 protein. Expression analysis of HvElf3 and Gigantea in mutant and wild-type plants demonstrated that mat-a mutations disturb the flowering pathway, leading to the early phenotype. Alleles of Mat-a therefore have important and demonstrated breeding value in barley but probably also in many other day-length-sensitive crop plants, where they may tune adaptation to different geographic regions and climatic conditions, a critical issue in times of global warming.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.