Evidence map›Paper›PMID 22371127›Full record

ArticleInternational urology and nephrology2012

Bacterial sepsis following prostatic biopsy.

Luca Carmignani, Stefano Picozzi, Matteo Spinelli, Salvatore Di Pierro, Gabriella Mombelli, Ercole Negri, Milvana Tejada, Paola Gaia, Elena Costa, Augusto Maggioni

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in International urology and nephrology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 47 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Luca CarmignaniUrology Department, IRCCS Policlinico San Donato, University of Milan, Via Morandi 30, 20097, San Donato Milanese, Milan, Italy.
Stefano Picozzi
Matteo Spinelli
Salvatore Di Pierro
Gabriella Mombelli
Ercole Negri
Milvana Tejada
Paola Gaia
Elena Costa
Augusto Maggioni
IRCCS Policlinico San Donato · ITUniversity of Milan · ITOspedale Maggiore · ITVilla Melitta · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDespite the recent innovations, complications of prostate biopsy can occur. The aim of this study was a prospective monitoring of major septic complications occurring after transrectal prostate biopsy, to describe their causing agents, to report the clinical course of these patients, and to give guidelines based on our personal experience.

methodsThis prospective study was carried out between January 2009 and September 2010. Complications were evaluated by telephone interviews.

resultsBetween January 2009 and September 2010, 447 (96.5%) completed the telephone interview. Urosepsis occurred in ten patients (2.2%) and in three cases evolved into septic shock. Of these ten patients, nine had a positive blood culture, of whom eight for Escherichia coli and one for Aeromonas hydrophila, Aeromonas caviae, and Aeromonas sobria. In seven cases, the E. coli isolated were resistant to fluoroquinolone and six produced an extended spectrum beta-lactamase. Six E. coli were classified as multidrug-resistant organisms. Of the 10 patients, one died after the onset of multiorgan failure. For the other nine, the mean time spent in the hospital was 9 days (range, 6-15 days).

conclusionsEscherichia coli are developing new drug resistances. Early recognition of patients who harbor MDRO E. coli in their rectum or in the urine could be an important strategy for preventing sepsis. If a patient who has recently undergone transrectal prostate biopsy shows clinical signs of sepsis in the 48 h, a multiresistant E. coli infection must be suspected. The patient must be admitted urgently to the hospital, and carbapenem antibiotic therapy should be started.

Indexed as

AgedAnti-Bacterial AgentsBiopsy, NeedleEscherichia coliEscherichia coli InfectionsFollow-Up StudiesHumansMaleMiddle AgedProspective StudiesProstateProstatic NeoplasmsSepsisAnti-Bacterial Agents

Identifiers

PMID22371127
OpenAlexW2031451507

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.