Evidence map›Paper›PMID 22371002›Full record

ArticleInternational journal of public health2012

Pandemic and seasonal vaccine coverage and effectiveness during the 2009-2010 pandemic influenza in an Italian adult population.

Simona Costanzo, Francesco Gianfagna, Mariarosaria Persichillo, Francesca De Lucia, Francesca D Lucia, Angelita Verna, Modjenar Djidingar, Sara Magnacca, Francesca Bracone, Marco Olivieri and 3 more

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In one paragraph

Article in International journal of public health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

  • Erratum issued
    Lucia, Francesca D [corrected to De Lucia, Francesca]
5 · Who and what money

Authors and funding

13 authors.

Simona CostanzoLaboratory of Genetic and Environmental Epidemiology, Research Laboratories, Fondazione di Ricerca e Cura Giovanni Paolo II, Largo Gemelli 1, 86100, Campobasso, Italy.
Francesco Gianfagna
Mariarosaria Persichillo
Francesca De Lucia
Francesca D Lucia
Angelita Verna
Modjenar Djidingar
Sara Magnacca
Francesca Bracone
Marco Olivieri
Maria Benedetta Donati
Giovanni de Gaetano
Licia Iacoviello

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the response to pandemic vaccination and seasonal and pandemic vaccine effectiveness (VE) in an Italian adult population, during the 2009-2010 influenza season.

methodsData were recorded by interviewing 19,275 subjects (≥35 years), randomly recruited from the general population of the Moli-sani project. Events [influenza-like illness (ILI), hospitalization and death], which had occurred between 1 November 2009 and 31 January 2010 were considered. VE was analyzed by multivariable Poisson regression analysis.

resultsPandemic vaccine coverage was very low (2.4%) in subjects at high-flu risk, aged 35-65 years (N = 8,048); there was no significant preventive effect of vaccine against ILI. Seasonal vaccine coverage was 26.6% in the whole population (63% in elderly and 21.9% in middle-aged subjects at high-flu risk). There was a higher risk to develop ILI in middle-age [VE: -17% (95% CI: -35,-1)] or at high flu-risk [VE: -17% (95% CI: -39, 2)] vaccinated groups.

conclusionsCoverage of pandemic vaccine was very low in a Southern Italy population, with no protective effect against ILI.

Indexed as

PandemicsAdultAgedFemaleHumansImmunization ProgramsInfluenza, HumanInterviews as TopicItalyMaleMiddle AgedPoisson DistributionProgram Evaluation

Identifiers

PMID22371002

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.