Evidence map›Paper›PMID 22370165›Full record

ArticleEpidemiology and infection2012

Molecular epidemiology of human Campylobacter jejuni shows association between seasonal and international patterns of disease.

N D McCarthy, I A Gillespie, A J Lawson, J Richardson, K R Neal, P R Hawtin, M C J Maiden, S J O'Brien

Abstract readComparative StudyMulticenter Study
In one paragraph

Article in Epidemiology and infection, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  18. Partial Failure of Milk Pasteurization as a Risk for the Transmission of Campylobacter From Cattle to Humans.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2015
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

N D McCarthyDepartment of Zoology, University of Oxford, Oxford, UK. noel.mccarthy@zoo.ox.ac.uk
I A Gillespie
A J Lawson
J Richardson
K R Neal
P R Hawtin
M C J Maiden
S J O'Brien

Funding

Wellcome Trust 087622
6 · The paper itself

Abstract

We sought to explain seasonality and other aspects of Campylobacter jejuni epidemiology by integrating population genetic and epidemiological analysis in a large 3-year longitudinal, two-centre, population-based study. Epidemiological information was collected for 1505 isolates, which were multilocus sequence-typed. Analyses compared pathogen population structure between areas, over time, and between clinical presentations. Pooled analysis was performed with published international datasets. Subtype association with virulence was not observed. UK sites had nearly identical C. jejuni populations. A clade formed by ST45 and ST283 clonal complexes showed a summer peak. This clade was common in a Finnish dataset but not in New Zealand and Australian collections, countries with less marked seasonality. The UK, New Zealand and Australian collections were otherwise similar. These findings map to known in-vitro differences of this clade. This identifies a target for studies to elucidate the drivers of the summer peak in human C. jejuni infection.

Indexed as

Multilocus Sequence TypingAdolescentAdultAustraliaCampylobacter InfectionsCampylobacter jejuniChi-Square DistributionEnglandFinlandGenotypeHumansLongitudinal StudiesMiddle AgedMolecular EpidemiologyNew ZealandPoisson Distribution

Identifiers

PMID22370165
PMCPMC3487483

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.