ArticleMembranes2011
Membrane Compartment Occupied by Can1 (MCC) and Eisosome Subdomains of the Fungal Plasma Membrane.
Article in Membranes, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Characterizing extracellular vesicles of human fungal pathogens.Nature microbiology · 2025Review
- Article
- The joint action of yeast eisosomes and membraneless organelles in response to ethanol stress.Heliyon · 2024Article
- SUR7 deletion inJournal of extracellular biology · 2023Article
- Complementation of an Eisosomal YeastJournal of fungi (Basel, Switzerland) · 2023Article
- Article
- A Snf1-related nutrient-responsive kinase antagonizes endocytosis in yeast.PLoS genetics · 2020Article
- N-glycosylation of Rim21 at an Unconventional Site Fine-tunes Its Behavior in the Plasma Membrane.Cell structure and function · 2020Article
- The Composition and the Structure of MCC/Eisosomes inFrontiers in microbiology · 2020Article
- Protein markers forJournal of extracellular vesicles · 2020Article
- The Gpr1-regulated Sur7 family protein Sfp2 is required for hyphal growth and cell wall stability in the mycoparasite Trichoderma atroviride.Scientific reports · 2018Article
- Steric exclusion and protein conformation determine the localization of plasma membrane transporters.Nature communications · 2018Article
- Glucose-ABL1-TOR Signaling Modulates Cell Cycle Tuning to Control Terminal Appressorial Cell Differentiation.PLoS genetics · 2017Article
- The Plasma Membrane Protein Nce102 Implicated in Eisosome Formation Rescues a Heme Defect in Mitochondria.The Journal of biological chemistry · 2016Article
- Identification of long-lived proteins retained in cells undergoing repeated asymmetric divisions.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Sphingolipids and lifespan regulation.Biochimica et biophysica acta · 2014Review
- A Pil1-Sle1-Syj1-Tax4 functional pathway links eisosomes with PI(4,5)P2 regulation.Journal of cell science · 2014Article
- Membrane domain formation-a key factor for targeted intracellular drug delivery.Frontiers in physiology · 2014Review
- Article
- An expanded view of the eukaryotic cytoskeleton.Molecular biology of the cell · 2013Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Studies on the budding yeast Saccharomyces cerevisiae have revealed that fungal plasma membranes are organized into different subdomains. One new domain termed MCC/eisosomes consists of stable punctate patches that are distinct from lipid rafts. The MCC/eisosome domains correspond to furrows in the plasma membrane that are about 300 nm long and 50 nm deep. The MCC portion includes integral membrane proteins, such as the tetraspanners Sur7 and Nce102. The adjacent eisosome includes proteins that are peripherally associated with the membrane, including the BAR domains proteins Pil1 and Lsp1 that are thought to promote membrane curvature. Genetic analysis of the MCC/eisosome components indicates these domains broadly affect overall plasma membrane organization. The mechanisms regulating the formation of MCC/eisosomes in model organisms will be reviewed as well as the role of these plasma membrane domains in fungal pathogenesis and response to antifungal drugs.
Identifiers
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Registered trials
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