ArticleJournal of oral microbiology2012
Virulence factors and antibiotic susceptibility in enterococci isolated from oral mucosal and deep infections.
Article in Journal of oral microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 83 citations in OpenAlex.
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- Explorative study on Lactobacillus species and their acid-producing capacity and anti-microbial activity in head and neck cancer patients.Clinical and experimental dental research · 2021Article
- Antibiofilm Efficacy of Luteolin Against Single and Dual Species ofFrontiers in microbiology · 2021Article
- Interactions betweenMicroorganisms · 2020Article
- Molecular Detection of Multidrug ResistantPathogens (Basel, Switzerland) · 2020Article
- Identification of Novel Bacteriophages with Therapeutic Potential That TargetInfection and immunity · 2019Article
- Candida albicans induces mucosal bacterial dysbiosis that promotes invasive infection.PLoS pathogens · 2019Article
- Emergence of multidrug resistance and extensive drug resistance among enterococcal clinical isolates in Egypt.Infection and drug resistance · 2019Article
- Candida Interactions with the Oral Bacterial Microbiota.Journal of fungi (Basel, Switzerland) · 2018Review
- Tipping the Balance:Journal of fungi (Basel, Switzerland) · 2018Review
- Comparative genome analysis reveals key genetic factors associated with probiotic property in Enterococcus faecium strains.BMC genomics · 2018Article
- Prevalence and Genetic Diversity ofFrontiers in microbiology · 2017Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study evaluates the presence of virulence factors and antibiotic susceptibility among enterococcal isolates from oral mucosal and deep infections.
methodsForty-three enterococcal strains from oral mucosal lesions and 18 from deep infections were isolated from 830 samples that were sent during 2 years to Oral Microbiology, University of Gothenburg, for analysis. The 61 strains were identified by 16S rDNA, and characterized by the presence of the virulence genes efa A (endocarditis gene), gel E (gelatinase gene), ace (collagen binding antigen gene), asa (aggregation substance gene), cyl A (cytolysin activator gene) and esp (surface adhesin gene), tested for the production of bacteriocins and presence of plasmids. MIC determination was performed using the E-test method against the most commonly used antibiotics in dentistry, for example, penicillin V, amoxicillin and clindamycin. Vancomycin was included in order to detect vancomycin-resistant enterococci (VRE) strains.
resultsSixty strains were identified as Enterococcus faecalis and one as Enterococcus faecium. All the virulence genes were detected in more than 93.3% (efa A and esp) of the E. faecalis strains, while the presence of phenotypic characteristics was much lower (gelatinase 10% and hemolysin 16.7%). Forty-six strains produced bacteriocins and one to six plasmids were detected in half of the isolates.
conclusionsEnterococcal strains from oral infections had a high virulence capacity, showed bacteriocin production and had numerous plasmids. They were generally susceptible to ampicillins but were resistant to clindamycin, commonly used in dentistry, and no VRE-strain was found.
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