ArticleThe Pan African medical journal2012
Determining the prevalence of human immunodeficiency virus-associated nephropathy (HIVAN) using proteinuria and ultrasound findings in a Nigerian paediatric HIV population.
Article in The Pan African medical journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.
- Prevalence of HIV-associated nephropathy in children: a systematic review with meta-analysis of studies published between 2004 and 2019.Pediatric nephrology (Berlin, Germany) · 2026Pooled it
- Kidney disease among children in sub-Saharan Africa: systematic review.Pediatric research · 2015Pooled it
- Kidney function parameters in South African children living with HIV on antiretroviral therapy.Antiviral therapy · 2026Observational
- Article
- Correlation between CD4 count and glomerular filtration rate or urine protein:creatinine ratio in human immunodeficiency virus-infected children.Kidney research and clinical practice · 2020Article
- HIV-Associated Nephropathy in Africa: Pathology, Clinical Presentation and Strategy for Prevention.Journal of clinical medicine research · 2018Review
- Renal abnormalities in a cohort of HIV-infected children and adolescents.Pediatric nephrology (Berlin, Germany) · 2016Article
- African origins and chronic kidney disease susceptibility in the human immunodeficiency virus era.World journal of nephrology · 2015Review
- The influence of HIV and schistosomiasis on renal function: a cross-sectional study among children at a hospital in Tanzania.PLoS neglected tropical diseases · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHIV associated nephropathy (HIVAN) is the most common form of chronic kidney disease resulting directly from HIV infection. The true prevalence of HIVAN in the paediatric population of West Africa is unknown, largely due to lack of surveillance and reporting of kidney disease in HIV positive patients.
methodsThis was a prospective study over a six month period( July to December 2008) conducted in the Infectious Disease Unit of the Department of Paediatrics, University of Uyo Teaching Hospital, Uyo, Nigeria involving all confirmed cases of paediatric HIV infection. Urine microalbuminuria using calculated urine albumin - creatinine ratio was determined and repeated in 4 weeks interval. CD4 count and renal ultrasonography was done for all the patients. The correlation of urine albumin - creatinine ratio with CD4 count, duration of treatment with highly active antiretroviral therapy (HAART) and association with clinical staging of the disease was also examined.
resultsFifty - nine (60.2%) were males, thirty - nine (39.8%) were females with male to female ratio of 1.5:1. The prevalence rate of 31.6% HIVAN was found, out of which 3.1% had abnormal ultrasound findings. There was a significant correlation between CD4 count and urine albumin - creatinine ratio (r=-0.22, p=0.03). There was no correlation between urine albumin - creatinine ratio and duration on HAART (r=-0.10, p=0.31).
conclusionScreening for microalbuminuria is essential for the early diagnosis and treatment of HIVAN in this age group.
Indexed as
Identifiers
22368756PMC3283028W1588048249What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.