Evidence map›Paper›PMID 22368730›Full record

ArticleGastrointestinal cancer research : GCR2011

Recent advances in the curative treatment of colorectal liver metastases.

Andreas Andreou, Thomas A Aloia, Antoine Brouquet, Jean-Nicolas Vauthey

Abstract read
In one paragraph

Article in Gastrointestinal cancer research : GCR, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Socioeconomic status influences the likelihood but not the outcome of liver resection for colorectal liver metastasis.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2015
    Article
  7. Article
  8. Article
  9. Article
  10. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andreas AndreouDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Thomas A Aloia
Antoine Brouquet
Jean-Nicolas Vauthey

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver resection provides the basis for curative treatment of colorectal liver metastases (CLM), achieving 5-year survival rates as high as 58%. Use of this approach is limited by the number of patients whose CLM are resectable at the time of initial presentation and the risk of early recurrence after surgery, justifying development of modern perioperative chemotherapy regimens. Chemotherapy-associated hepatotoxicity led to development of standardized treatment strategies that balance the duration and timing of preoperative chemotherapy to minimize postoperative morbidity. The current challenge in the effort to offer curative treatment for CLM is selection of patients who will most benefit from an aggressive surgical approach. New end points of preoperative chemotherapy such as pathologic response and new radiologic response criteria have been evaluated as predictive factors for survival after liver resection and provide useful support in selecting patients for surgery.

Identifiers

PMID22368730
PMCPMC3283006

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.