Evidence map›Paper›PMID 22368447›Full record

ArticleTherapeutics and clinical risk management2012

Coronary artery disease in Africa and the Middle East.

Wael Almahmeed, Mohamad Samir Arnaout, Rafik Chettaoui, Mohsen Ibrahim, Mohamed Ibrahim Kurdi, Mohamed Awad Taher, Giuseppe Mancia

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Therapeutics and clinical risk management, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05536271 phase2completednot on this mapstarted 2021, after this paper: background citation

Pharmacogenetic Study of Bisoprolol in Egyptian Patients With Acute Coronary Syndrome

TypeinterventionalSponsorDamanhour UniversityRan2021 to 2022Enrolled127ConditionsAcute Coronary SyndromeArmsBisoprolol Fumarate
NCT05536284 phase2completednot on this mapstarted 2021, after this paper: background citation

Potential Drug Interactions With Bisoprolol in Egyptian Patients With Acute Coronary Syndrome

TypeinterventionalSponsorDamanhour UniversityRan2021 to 2022Enrolled128ConditionsAcute Coronary SyndromeArmsBisoprolol Fumarate Tablets
3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it, 104 citations in OpenAlex.

  1. Pooled it
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  17. An Emerging Syndemic of Smoking and Cardiopulmonary Diseases in People Living with HIV in Africa.International journal of environmental research and public health · 2021
    Article
  18. Article
  19. Article
  20. Low Protein Z Level: A Thrombophilic Risk Biomarker for Acute Coronary Syndrome.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 5 countries.

Wael AlmahmeedHeart and Vascular Institute, Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates.
Mohamad Samir Arnaout
Rafik Chettaoui
Mohsen Ibrahim
Mohamed Ibrahim Kurdi
Mohamed Awad Taher
Giuseppe Mancia
American University of Beirut Medical Center · LBCairo University · EGIRCCS Istituto Auxologico Italiano · ITKing Khalid University · SAShaikh Khalifa Medical City · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Countries in Africa and the Middle East bear a heavy burden from cardiovascular disease. The prevalence of coronary heart disease is promoted in turn by a high prevalence of cardiovascular risk factors, particularly smoking, hypertension, dyslipidemia, diabetes, and sedentary lifestyles. Patients in Africa and the Middle East present with myocardial infarction at a younger age, on average, compared with patients elsewhere. The projected future burden of mortality from coronary heart disease in Africa and the Middle East is set to outstrip that observed in other geographical regions. Recent detailed nationally representative epidemiological data are lacking for many countries, and high proportions of transient expatriate workers in countries such as Saudi Arabia and the United Arab Emirates complicate the construction of such datasets. However, the development of national registries in some countries is beginning to reveal the nature of coronary heart disease. Improving lifestyles (reducing calorie intake and increasing physical activity) in patients in the region will be essential, although cultural and environmental barriers will render this difficult. Appropriate prescribing of pharmacologic treatments is essential in the prevention and management of cardiovascular disease. In particular, recent controversies relating to the therapeutic profile of beta-blockers may have reduced their use. The current evidence base suggests that beta-blockers are as effective as other therapies in preventing cardiovascular disease and that concerns relating to their use in hypertension and cardiovascular disease have been overstated.

Indexed as

beta-blockerscardiovascular diseasecardiovascular risk factorscoronary heart diseaseheart failure

Identifiers

PMID22368447
PMCPMC3284217
OpenAlexW2095225049

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.