Evidence map›Paper›PMID 22368416›Full record

ArticleJournal of pharmacology & pharmacotherapeutics2012

Evaluation of the aphrodisiac activity of Tribulus terrestris Linn. in sexually sluggish male albino rats.

Surender Singh, Vinod Nair, Yogendra K Gupta

Open access · greenAbstract read
In one paragraph

Article in Journal of pharmacology & pharmacotherapeutics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 3 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 92 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Effects ofInternational journal of environmental research and public health · 2022
    Pooled it
  4. The Effects of 6 Weeks ofNutrients · 2021
    Trial
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Heliyon · 2024
    Article
  11. Article
  12. Veterinary research forum : an international quarterly journal · 2023
    Article
  13. Article
  14. Comparative efficacy of Gum Arabic (Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2020
    Article
  15. Review
  16. Review
  17. Evaluation of cytological and genetic effects ofSaudi journal of biological sciences · 2019
    Article
  18. African health sciences · 2018
    Article
  19. Journal of sport and health science · 2017
    Article
  20. Tribulus terrestris Extract Improves Human Sperm Parameters In Vitro.Journal of evidence-based complementary & alternative medicine · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Surender SinghDepartment of Pharmacology, All India Institute of Medical Sciences, New Delhi 110 029, India.
Vinod Nair
Yogendra K Gupta
All India Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo study the effect of acute and repeated dose administration of lyophilized aqueous extract of the dried fruits of Tribulus terrestris (LAET) on sexual function in sexually sluggish male albino rats. MATERIALS AND

methodsAphrodisiac activity of the test drug was evaluated in terms of exhibited sexual behavior. In order to assess the effect of chronic T. terrestris exposure on the hypothalamus--pituitary--gonadal axis, testosterone level estimation and sperm count were carried out. Twenty-eight-day oral toxicity studies were carried out to evaluate the long-term effects of the LAET administration on different body systems.

resultsA dose-dependent improvement in sexual behavior was observed with the LAET treatment as characterized by an increase in mount frequency, intromission frequency, and penile erection index, as well as a decrease in mount latency, intromission latency, and ejaculatory latency. The enhancement of sexual behavior was more prominent on chronic administration of LAET. Chronic administration of LAET produced a significant increase in serum testosterone levels with no significant effect on the sperm count. No overt body system dysfunctions were observed in 28-day oral toxicity study.

conclusionsFindings of the present study validate the traditional use of T. terrestris as a sexual enhancer in the management of sexual dysfunction in males.

Indexed as

Aphrodisiacpenile erection indexsexual behaviortestosteroneTribulus terrestris

Identifiers

PMID22368416
PMCPMC3284036
OpenAlexW2092918931

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.