ArticleBioinformatics (Oxford, England)2012
SiteComp: a server for ligand binding site analysis in protein structures.
Article in Bioinformatics (Oxford, England), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Hybrid protein-ligand binding residue prediction with protein language models: does the structure matter?Bioinformatics (Oxford, England) · 2025Article
- VirtuousPocketome: a computational tool for screening protein-ligand complexes to identify similar binding sites.Scientific reports · 2024Article
- Nontoxic and Naturally Occurring Active Compounds as Potential Inhibitors of Biological Targets inInternational journal of molecular sciences · 2022Article
- In Silico Methods for Identification of Potential Active Sites of Therapeutic Targets.Molecules (Basel, Switzerland) · 2022Review
- GraphSite: Ligand Binding Site Classification with Deep Graph Learning.Biomolecules · 2022Article
- CHARMM-GUIJournal of chemical information and modeling · 2021Article
- Exploring the computational methods for protein-ligand binding site prediction.Computational and structural biotechnology journal · 2020Review
- Biological and functional relevance of CASP predictions.Proteins · 2018Article
- Crystal Structures of the SpoIID Lytic Transglycosylases Essential for Bacterial Sporulation.The Journal of biological chemistry · 2016Article
- Considerations of Protein Subpockets in Fragment-Based Drug Design.Chemical biology & drug design · 2016Article
- Proteins and Their Interacting Partners: An Introduction to Protein-Ligand Binding Site Prediction Methods.International journal of molecular sciences · 2015Review
- Creation of a free, Internet-accessible database: the Multiple Target Ligand Database.Journal of cheminformatics · 2015Article
- AFAL: a web service for profiling amino acids surrounding ligands in proteins.Journal of computer-aided molecular design · 2014Article
- Drug-Like Protein-Protein Interaction Modulators: Challenges and Opportunities for Drug Discovery and Chemical Biology.Molecular informatics · 2014Review
- Pocket-based drug design: exploring pocket space.The AAPS journal · 2013Review
- Computer-Aided Protein Directed Evolution: a Review of Web Servers, Databases and other Computational Tools for Protein Engineering.Computational and structural biotechnology journal · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
motivationComputational characterization of ligand-binding sites in proteins provides preliminary information for functional annotation, protein design and ligand optimization. SiteComp implements binding site analysis for comparison of binding sites, evaluation of residue contribution to binding sites and identification of sub-sites with distinct molecular interaction properties. AVAILABILITY AND IMPLEMENTATION: The SiteComp server and tutorials are freely available at http://sitecomp.sanchezlab.org.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.