ReviewAmerican journal of hematology2012
Current and future management of pediatric venous thromboembolism.
Review in American journal of hematology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07129395 (Optimizing Measurement of Anticoagulation Adherence), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Optimizing Measurement of Anticoagulation Adherence
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Management of congenital nephrotic syndrome: consensus recommendations of the ERKNet-ESPN Working Group.Nature reviews. Nephrology · 2021Guideline
- Article
- Thrombosis in Chronic Kidney Disease in Children.Diagnostics (Basel, Switzerland) · 2022Article
- Assessment of provider practices regarding venous thromboembolism management and prevention in pediatric acute leukemia patients.Journal of thrombosis and thrombolysis · 2021Article
- Role of direct oral anticoagulants in patients with kidney disease.Kidney international · 2020Review
- Venous thromboembolism in children undergoing surgery: incidence, risk factors and related adverse events.World journal of pediatric surgery · 2020Article
- Article
- A multi-national trial of a direct oral anticoagulant in children with cardiac disease: Design and rationale of the Safety of ApiXaban On Pediatric Heart disease On the preventioN of Embolism (SAXOPHONE) study.American heart journal · 2019Article
- Venous thromboembolism risk factors in a pediatric trauma population.Pediatric surgery international · 2019Article
- Venous thromboembolism following inpatient pediatric surgery: Analysis of 153,220 patients.Journal of pediatric surgery · 2019Article
- Pulmonary embolism presenting with acute abdominal pain in a girl with stable ankle fracture and inherited antithrombin deficiency.Blood research · 2018Article
- Rationale and design of a phase III safety trial of idarucizumab in children receiving dabigatran etexilate for venous thromboembolism.Research and practice in thrombosis and haemostasis · 2018Article
- Venous thromboembolism in children and adolescents.Blood research · 2016Article
- The non-immunosuppressive management of childhood nephrotic syndrome.Pediatric nephrology (Berlin, Germany) · 2016Review
- Current Clinical Trials on the Use of Direct Oral Anticoagulants in the Pediatric Population.Cardiology and therapy · 2016Review
- Complications and 30-day Outcomes Associated With Venous Thromboembolism in the Pediatric Orthopaedic Surgical Population.The Journal of the American Academy of Orthopaedic Surgeons · 2016Article
- Healthcare burden of venous thromboembolism in childhood chronic renal diseases.Pediatric nephrology (Berlin, Germany) · 2015Article
- Development of a pediatric-specific clinical probability tool for diagnosis of venous thromboembolism: a feasibility study.Pediatric research · 2015Article
- Risk factors for hospital-sssociated venous thromboembolism in the neonatal intensive care unit.Thrombosis research · 2014Article
- Venous thromboembolism in pediatric nephrotic syndrome.Pediatric nephrology (Berlin, Germany) · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Venous thromboembolism (VTE) is an increasingly common complication encountered in tertiary care pediatric settings. The purpose of this review is to summarize the epidemiology, current and emerging pharmacotherapeutic options, and management of this disease. Over 70% of VTE occur in children with chronic diseases. Although they are seen in children of all ages, adolescents are at greatest risk. Pediatric VTE is associated with an increased risk of in-hospital mortality; recurrent VTE and post-thrombotic syndrome are commonly seen in survivors. In recent years, anticoagulation with low molecular weight heparin has emerged as the mainstay of therapy, but compliance is limited by its onerous subcutaneous administration route. New anticoagulants either already approved for use in adults or in the pipeline offer the possibility of improved dose stability and oral routes of administration. Current recommended anticoagulation course durations are derived from very limited case series and cohort data, or extrapolations from adult literature. However, the pathophysiologic underpinnings of pediatric VTE are dissimilar from those seen in adults and are often variable within groups of pediatric patients. Clinical studies and trials in pediatric VTE are underway which will hopefully improve the quality of evidence from which therapeutic guidelines are derived.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.