Evidence map›Paper›PMID 22367584›Full record

ArticleEndocrine2012

Nesfatin-1 and other hormone alterations in polycystic ovary syndrome.

Rulin Deniz, Bilgin Gurates, Suleyman Aydin, Husnu Celik, Ibrahim Sahin, Yakup Baykus, Zekiye Catak, Aziz Aksoy, Cihan Citil, Sami Gungor

Abstract read
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In one paragraph

Article in Endocrine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  6. Article
  7. Review
  8. Review of Novel Potential Insulin Resistance Biomarkers in PCOS Patients-The Debate Is Still Open.International journal of environmental research and public health · 2022
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
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  15. Article
  16. Serum nesfatin-1 is reduced in type 2 diabetes mellitus patients with peripheral arterial disease.Medical science monitor : international medical journal of experimental and clinical research · 2015
    Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rulin DenizDepartment of Obstetrics and Gynecology, Firat University Hospital, Elazig, Turkey.
Bilgin Gurates
Suleyman Aydin
Husnu Celik
Ibrahim Sahin
Yakup Baykus
Zekiye Catak
Aziz Aksoy
Cihan Citil
Sami Gungor

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polycystic ovary syndrome (PCOS) is commonly characterised by obesity, insulin resistance (IR), hyperandrogenemia and hirsutism. Nesfatin-1 a recently discovered hormone, acts upon energy balance, glucose metabolism, obesity and probably gonadal functions. This study was to evaluate the circulating levels of nesfatin-1 in patients with PCOS (n = 30) and in age and body mass index (BMI)-matched controls (n = 30). PCOS patients had significantly lower levels of nesfatin-1 (0.88 ± 0.36 ng/mL) than healthy controls (2.22 ± 1.14 ng/mL). PCOS patients also had higher gonadotropin and androgen plasma concentrations, Ferriman-Gallwey scores, blood glucose levels and a homeostasis model of assessment-IR index (HOMA-IR) index than in healthy women. Correlation tests in PCOS subjects detected a negative correlation between nesfatin-1 levels and BMI, fasting blood glucose, insulin levels and a HOMA-IR index. Lower nesfatin-1 concentration may plays a very important role in the development of PCOS.

Indexed as

AdultBlood GlucoseBody Mass IndexCalcium-Binding ProteinsDNA-Binding ProteinsFemaleHormonesHumansInsulinInsulin ResistanceLipidsNerve Tissue ProteinsNucleobindinsPolycystic Ovary SyndromeYoung AdultBlood GlucoseCalcium-Binding ProteinsDNA-Binding ProteinsHormonesInsulinLipidsNerve Tissue ProteinsNUCB2 protein, humanNucleobindins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.