ArticleEuropean radiology2012
Current status and guidelines for the assessment of tumour vascular support with dynamic contrast-enhanced computed tomography.
Article in European radiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 1 of them a synthesis that pooled it.
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Who cites it
77 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Quantitative imaging: systematic review of perfusion/flow phantoms.European radiology experimental · 2020Pooled it
- A prospective clinical trial on sorafenib treatment of hepatocellular carcinoma before liver transplantation.BMC cancer · 2019Trial
- An application study of low-dose computed tomography perfusion imaging for evaluation of the efficacy of neoadjuvant chemotherapy for advanced gastric adenocarcinoma.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2018Trial
- Multiparametric imaging of patient and tumour heterogeneity in non-small-cell lung cancer: quantification of tumour hypoxia, metabolism and perfusion.European journal of nuclear medicine and molecular imaging · 2016Trial
- Non-invasive determination of pulmonary hypertension with dynamic contrast-enhanced computed tomography: a pilot study.European radiology · 2014Trial
- Contrast-ultrasound dispersion imaging for renal cell carcinoma diagnostics.The ultrasound journal · 2025Article
- DCE-CT parameters as new functional imaging biomarkers at baseline and during immune checkpoint inhibitor therapy in patients with lung cancer - a feasibility study.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024Article
- Diagnostic accuracy of low-dose dual-input computed tomography perfusion in the differential diagnosis of pulmonary benign and malignant ground-glass nodules.Scientific reports · 2024Article
- Pancreatic CT perfusion: quantitative meta-analysis of disease discrimination, protocol development, and effect of CT parameters.Insights into imaging · 2023Article
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- Prognostic value of preoperative enhanced computed tomography as a quantitative imaging biomarker in pancreatic cancer.World journal of gastroenterology · 2022Article
- Dynamic contrast-enhanced (DCE) imaging: state of the art and applications in whole-body imaging.Japanese journal of radiology · 2022Review
- Recent Advance in Biological Responsive Nanomaterials for Biosensing and Molecular Imaging Application.International journal of molecular sciences · 2022Review
- CT perfusion imaging can detect residual lung tumor early after radiofrequency ablation: a preliminary animal study on both tumoral and peri-tumoral region assessment.Journal of thoracic disease · 2022Article
- FDG-PET/CT in colorectal cancer: potential for vascular-metabolic imaging to provide markers of prognosis.European journal of nuclear medicine and molecular imaging · 2021Observational
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- Blood Volume as a new functional image-based biomarker of progression in metastatic renal cell carcinoma.Scientific reports · 2021Article
- Prognostic value of DCE-CT-derived blood volume and flow compared to core biopsy microvessel density in patients with metastatic renal cell carcinoma.European radiology experimental · 2021Article
- Advanced CT techniques for assessing hepatocellular carcinoma.La Radiologia medica · 2021Review
17 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
Dynamic contrast-enhanced computed tomography (DCE-CT) assesses the vascular support of tumours through analysis of temporal changes in attenuation in blood vessels and tissues during a rapid series of images acquired with intravenous administration of iodinated contrast material. Commercial software for DCE-CT analysis allows pixel-by-pixel calculation of a range of validated physiological parameters and depiction as parametric maps. Clinical studies support the use of DCE-CT parameters as surrogates for physiological and molecular processes underlying tumour angiogenesis. DCE-CT has been used to provide biomarkers of drug action in early phase trials for the treatment of a range of cancers. DCE-CT can be appended to current imaging assessments of tumour response with the benefits of wide availability and low cost. This paper sets out guidelines for the use of DCE-CT in assessing tumour vascular support that were developed using a Delphi process. Recommendations encompass CT system requirements and quality assurance, radiation dosimetry, patient preparation, administration of contrast material, CT acquisition parameters, terminology and units, data processing and reporting. DCE-CT has reached technical maturity for use in therapeutic trials in oncology. The development of these consensus guidelines may promote broader application of DCE-CT for the evaluation of tumour vascularity. Key Points • DCE-CT can robustly assess tumour vascular support • DCE-CT has reached technical maturity for use in therapeutic trials in oncology • This paper presents consensus guidelines for using DCE-CT in assessing tumour vascularity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.