Evidence map›Paper›PMID 22365460›Full record

ArticleJournal of the American Academy of Child and Adolescent Psychiatry2012

Parsing heterogeneity in autism spectrum disorders: visual scanning of dynamic social scenes in school-aged children.

Katherine Rice, Jennifer M Moriuchi, Warren Jones, Ami Klin

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Academy of Child and Adolescent Psychiatry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 97 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
97citing papers in PubMed, 2 pooled it
9.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

97 citing papers in PubMed, 2 syntheses or guidelines pooled it, 229 citations in OpenAlex.

  1. Gaze and social functioning associations in autism spectrum disorder: A systematic review and meta-analysis.Autism research : official journal of the International Society for Autism Research · 2022
    Pooled it
  2. Pooled it
  3. Development of an Objective Autism Risk Index Using Remote Eye Tracking.Journal of the American Academy of Child and Adolescent Psychiatry · 2016
    Trial
  4. Article
  5. Audio-Visual Speech Synchrony Impacts Gaze Patterns in Autism.Journal of autism and developmental disorders · 2025
    Article
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  9. The impact of attention to social information on the development of socialization in childhood.Scandinavian journal of child and adolescent psychiatry and psychology · 2025
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37 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Katherine RiceUniversity of Maryland, MD, USA.
Jennifer M Moriuchi
Warren Jones
Ami Klin
Children's Healthcare of Atlanta · USEmory University · USUniversity of Maryland, College Park · US

Funding

Eye-Tracking Studies of Social Visual Pursuit in AutismR01HD042127 · NICHD · YALE UNIVERSITY · PI KLIN, AMI · 2002 to 2006
$1.8M
NICHD NIH HHS R01 HD042127NICHD NIH HHS R01HD42127
6 · The paper itself

Abstract

objectiveTo examine patterns of variability in social visual engagement and their relationship to standardized measures of social disability in a heterogeneous sample of school-aged children with autism spectrum disorders (ASD).

methodEye-tracking measures of visual fixation during free-viewing of dynamic social scenes were obtained for 109 children with ASD (mean age, 10.2 ± 3.2 years), 37 of whom were matched with 26 typically-developing (TD) children (mean age, 9.5 ± 2.2 years) on gender, age, and IQ. The smaller subset allowed between-group comparisons, whereas the larger group was used for within-group examinations of ASD heterogeneity.

resultsBetween-group comparisons revealed significantly attenuated orientation to socially salient aspects of the scenes, with the largest effect size (Cohen's d = 1.5) obtained for reduced fixation on faces. Within-group analyses revealed a robust association between higher fixation on the inanimate environment and greater social disability. However, the associations between fixation on the eyes and mouth and social adaptation varied greatly, even reversing, when comparing different cognitive profile subgroups.

conclusionsAlthough patterns of social visual engagement with naturalistic social stimuli are profoundly altered in children with ASD, the social adaptivity of these behaviors varies for different groups of children. This variation likely represents different patterns of adaptation and maladaptation that should be traced longitudinally to the first years of life, before complex interactions between early predispositions and compensatory learning take place. We propose that variability in these early mechanisms of socialization may serve as proximal behavioral manifestations of genetic vulnerabilities.

Indexed as

Child Development Disorders, PervasivePhotic StimulationAdolescentChildEye MovementsFemaleFixation, OcularHumansMaleMotion PicturesNeuropsychological TestsPersonality DevelopmentPsychiatric Status Rating ScalesSocial AdjustmentVisual Perception

Identifiers

PMID22365460
PMCPMC3306820
OpenAlexW2082605724

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.