Evidence map›Paper›PMID 22364816›Full record

ArticleContraception2012

Contraindications to progestin-only oral contraceptive pills among reproductive-aged women.

Kari White, Joseph E Potter, Kristine Hopkins, Leticia Fernández, Jon Amastae, Daniel Grossman

Abstract read
In one paragraph

Article in Contraception, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 59 citations in OpenAlex.

  1. Trial
  2. Review
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Kari WhiteHealth Care Organization and Policy, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Joseph E Potter
Kristine Hopkins
Leticia Fernández
Jon Amastae
Daniel Grossman
The University of Texas at Austin · USIbis Reproductive Health · USThe University of Texas at El Paso · USUniversity of Alabama at Birmingham · USUniversity of Pretoria · ZA

Funding

Oral Contraceptive Use along the US-Mexico BorderR01HD047816 · NICHD · UNIVERSITY OF TEXAS AUSTIN · PI POTTER, JOSEPH E · 2005 to 2009
$2.3M
NICHD NIH HHS R01 HD047816NICHD NIH HHS R01HD047816
6 · The paper itself

Abstract

backgroundProgestin-only oral contraceptive pills (POPs) have fewer contraindications to use compared to combined pills. However, the overall prevalence of contraindications to POPs among reproductive-aged women has not been assessed. STUDY

designWe collected information on contraindications to POPs in two studies: (1) the Self-Screening Study, a sample of 1267 reproductive-aged women in the general population in El Paso, TX, and (2) the Prospective Study of OC Users, a sample of current oral contraceptive (OC) users who obtained their pills in El Paso clinics (n=532) or over the counter (OTC) in Mexican pharmacies (n=514). In the Self-Screening Study, we also compared women's self-assessment of contraindications using a checklist to a clinician's evaluation.

resultsOnly 1.6% of women in the Self-Screening Study were identified as having at least one contraindication to POPs. The sensitivity of the checklist for identifying women with at least one contraindication was 75.0% [95% confidence interval (CI): 50.6%-90.4%], and the specificity was 99.4% (95% CI: 98.8%-99.7%). In total, 0.6% of women in the Prospective Study of OC Users reported having any contraindication to POPs. There were no significant differences between clinic and OTC users.

conclusionThe prevalence of contraindications to POPs was very low in these samples. POPs may be the best choice for the first OTC oral contraceptive in the United States.

Indexed as

Contraceptives, Oral, HormonalDiagnostic Self EvaluationProgestinsAdolescentAdultAnticonvulsantsAntitubercular AgentsBreast NeoplasmsChecklistContraindicationsDrug InteractionsFemaleHumansLiver DiseasesMexicoMiddle AgedAnticonvulsantsAntitubercular AgentsContraceptives, Oral, HormonalNonprescription DrugsPrescription DrugsProgestins

Identifiers

PMID22364816
PMCPMC3368072
OpenAlexW2078971459

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.