ArticlePloS one2012
Health system resource gaps and associated mortality from pandemic influenza across six Asian territories.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 5 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Building resource constraints and feasibility considerations in mathematical models for infectious disease: A systematic literature review.Epidemics · 2021Pooled it
- Hospitalization Fatality Risk of Influenza A(H1N1)pdm09: A Systematic Review and Meta-Analysis.American journal of epidemiology · 2015Pooled it
- Simulation models for socioeconomic inequalities in health: a systematic review.International journal of environmental research and public health · 2013Pooled it
- Case fatality risk of influenza A (H1N1pdm09): a systematic review.Epidemiology (Cambridge, Mass.) · 2013Pooled it
- Health systems' "surge capacity": state of the art and priorities for future research.The Milbank quarterly · 2013Pooled it
- A comparison of national seasonal influenza treatment guidelines across the Asia Pacific region.PLOS global public health · 2025Article
- Accuracy of US CDC COVID-19 forecasting models.Frontiers in public health · 2024Article
- Cobalt compensator-based IMRT device: A treatment planning study of head and neck cases.Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) · 2023Article
- Article
- Confronting the threat of bioterrorism: realities, challenges, and defensive strategies.The Lancet. Infectious diseases · 2019Review
- Organisation of primary health care in the Asia-Pacific region: developing a prioritised research agenda.BMJ global health · 2019Review
- Healthcare infrastructure capacity to respond to severe acute respiratory infection (SARI) and sepsis in Vietnam: A low-middle income country.Journal of critical care · 2017Article
- Predictive accuracy of particle filtering in dynamic models supporting outbreak projections.BMC infectious diseases · 2017Article
- The safety and immunogenicity of a MF59-adjuvanted H5N1 prepandemic influenza vaccine in healthy adults primed with homologous or heterologous H5N1 vaccines: an observational study.BMC infectious diseases · 2014Observational
- Distribution of selected healthcare resources for influenza pandemic response in Cambodia.International journal for equity in health · 2013Article
- Human H5N1 influenza infections in Cambodia 2005-2011: case series and cost-of-illness.BMC public health · 2013Article
- Prospects for emerging infections in East and southeast Asia 10 years after severe acute respiratory syndrome.Emerging infectious diseases · 2013Review
- An analysis of health system resources in relation to pandemic response capacity in the Greater Mekong Subregion.International journal of health geographics · 2012Article
- Cost-effectiveness analysis of pandemic influenza preparedness: what's missing?Bulletin of the World Health Organization · 2012Article
- Development of a resource modelling tool to support decision makers in pandemic influenza preparedness: The AsiaFluCap Simulator.BMC public health · 2012Article
Corrections and comments
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSoutheast Asia has been the focus of considerable investment in pandemic influenza preparedness. Given the wide variation in socio-economic conditions, health system capacity across the region is likely to impact to varying degrees on pandemic mitigation operations. We aimed to estimate and compare the resource gaps, and potential mortalities associated with those gaps, for responding to pandemic influenza within and between six territories in Asia. METHODS AND
findingsWe collected health system resource data from Cambodia, Indonesia (Jakarta and Bali), Lao PDR, Taiwan, Thailand and Vietnam. We applied a mathematical transmission model to simulate a "mild-to-moderate" pandemic influenza scenario to estimate resource needs, gaps, and attributable mortalities at province level within each territory. The results show that wide variations exist in resource capacities between and within the six territories, with substantial mortalities predicted as a result of resource gaps (referred to here as "avoidable" mortalities), particularly in poorer areas. Severe nationwide shortages of mechanical ventilators were estimated to be a major cause of avoidable mortalities in all territories except Taiwan. Other resources (oseltamivir, hospital beds and human resources) are inequitably distributed within countries. Estimates of resource gaps and avoidable mortalities were highly sensitive to model parameters defining the transmissibility and clinical severity of the pandemic scenario. However, geographic patterns observed within and across territories remained similar for the range of parameter values explored.
conclusionsThe findings have important implications for where (both geographically and in terms of which resource types) investment is most needed, and the potential impact of resource mobilization for mitigating the disease burden of an influenza pandemic. Effective mobilization of resources across administrative boundaries could go some way towards minimizing avoidable deaths.
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