ArticlePloS one2012
Defensome against toxic diatom aldehydes in the sea urchin Paracentrotus lividus.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 53 citations in OpenAlex.
- Toxigenic effects of sponges and benthic diatoms on marine invertebrates and their possible biotechnological applications.Scientific reports · 2024Article
- Controlled uptake of PFOA in adult specimens of Paracentrotus lividus and evaluation of gene expression in their gonads and embryos.Environmental science and pollution research international · 2023Article
- Morphologic and genic effects of waste pollution on the reproductive physiology ofFrontiers in physiology · 2023Article
- Gene Expression Detects the Factors Influencing the Reproductive Success and the Survival Rates ofInternational journal of molecular sciences · 2022Article
- PAHs and PCBs Affect Functionally Intercorrelated Genes in the Sea UrchinInternational journal of molecular sciences · 2021Article
- Sub-Chronic Effects of Slight PAH- and PCB-Contaminated Mesocosms inInternational journal of molecular sciences · 2021Article
- Biochemical Characterization of a Novel Redox-Regulated Metacaspase in a Marine Diatom.Frontiers in microbiology · 2021Article
- Diatom-Derived Polyunsaturated Aldehydes Activate Similar Cell Death Genes in Two Different Systems: Sea Urchin Embryos and Human Cells.International journal of molecular sciences · 2020Article
- Multiple Roles of Diatom-Derived Oxylipins within Marine Environments and Their Potential Biotechnological Applications.Marine drugs · 2020Review
- Combined Effects of Diatom-Derived Oxylipins on the Sea UrchinInternational journal of molecular sciences · 2020Article
- Molecular and Morphological Toxicity of Diatom-Derived Hydroxyacid Mixtures to Sea UrchinMarine drugs · 2019Article
- Toxicity of diatom-derived polyunsaturated aldehyde mixtures on sea urchin Paracentrotus lividus development.Scientific reports · 2019Article
- Diatom bloom-derived biotoxins cause aberrant development and gene expression in the appendicularian chordateCommunications biology · 2018Article
- Genome of the Asian longhorned beetle (Anoplophora glabripennis), a globally significant invasive species, reveals key functional and evolutionary innovations at the beetle-plant interface.Genome biology · 2016Article
- New insights into negative effects of lithium on sea urchin Paracentrotus lividus embryos.Scientific reports · 2016Article
- First Morphological and Molecular Evidence of the Negative Impact of Diatom-Derived Hydroxyacids on the Sea Urchin Paracentrotus lividus.Toxicological sciences : an official journal of the Society of Toxicology · 2016Article
- Subtle reproductive impairment through nitric oxide-mediated mechanisms in sea urchins from an area affected by harmful algal blooms.Scientific reports · 2016Article
- Article
- The diatom-derived aldehyde decadienal affects life cycle transition in the ascidian Ciona intestinalis through nitric oxide/ERK signalling.Open biology · 2015Article
- Maternal Exposure to Cadmium and Manganese Impairs Reproduction and Progeny Fitness in the Sea Urchin Paracentrotus lividus.PloS one · 2015Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many diatom species produce polyunsaturated aldehydes, such as decadienal, which compromise embryonic and larval development in benthic organisms. Here newly fertilized Paracentrotus lividus sea urchins were exposed to low concentration of decadienal and the expression levels of sixteen genes, implicated in a broad range of functional responses, were followed by Real Time qPCR in order to identify potential decadienal targets. We show that at low decadienal concentrations the sea urchin Paracentrotus lividus places in motion different classes of genes to defend itself against this toxic aldehyde, activating hsp60 and two proteases, hat and BP10, at the blastula stage and hsp56 and several other genes (14-3-3ε, p38 MAPK, MTase, and GS) at the prism stage. At this latter stage all genes involved in skeletogenesis (Nec, uni, SM50 and SM30) were also down-expressed, following developmental abnormalities that mainly affected skeleton morphogenesis. Moreover, sea urchin embryos treated with increasing concentrations of decadienal revealed a dose-dependent response of activated target genes. Finally, we suggest that this orchestrated defense system against decadienal represents part of the chemical defensome of P. lividus affording protection from environmental toxicants.
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