ArticlePloS one2012
Verticillium longisporum infection affects the leaf apoplastic proteome, metabolome, and cell wall properties in Arabidopsis thaliana.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
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Who cites it
53 citing papers in PubMed, 148 citations in OpenAlex.
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- Apoplast Metabolomics Profiling Reveals Nitrogen-Dependent Modulation of Plant-Pathogen Interactions.Molecular plant pathology · 2025Article
- Beyond the surface: the plant secretome as a bridge between the cell and its environment.Planta · 2025Review
- Nitrate transporter protein NPF5.12 and major latex-like protein MLP6 are important defense factors against Verticillium longisporum.Journal of experimental botany · 2024Article
- Identification of mungbean yellow mosaic India virus and susceptibility-related metabolites in the apoplast of mung bean leaves.Plant cell reports · 2024Article
- Integrated Proteomics and Metabolomics of Safflower Petal Wilting and Seed Development.Biomolecules · 2024Article
- Genome-wide identification and analysis of a cotton secretome reveals its role in resistance against Verticillium dahliae.BMC biology · 2023Article
- Extracellular RNA: mechanisms of secretion and potential functions.Journal of experimental botany · 2023Article
- Untargeted Metabolomics Profiling of Arabidopsis WT,Metabolites · 2022Article
- Specific Roles of Lipoxygenases in Development and Responses to Stress in Plants.Plants (Basel, Switzerland) · 2022Review
- Extracellular Glycolytic Activities in Root EndophyticMicroorganisms · 2022Article
- Transcriptome and metabolite profiling reveals the effects of Funneliformis mosseae on the roots of continuously cropped soybeans.BMC plant biology · 2020Article
- Hop Polyphenols in Relation to Verticillium Wilt Resistance and Their Antifungal Activity.Plants (Basel, Switzerland) · 2020Article
- The Apoplast: A Key Player in Plant Survival.Antioxidants (Basel, Switzerland) · 2020Review
- Lolium perenne apoplast metabolomics for identification of novel metabolites produced by the symbiotic fungus Epichloë festucae.The New phytologist · 2020Article
- Suppression of abscisic acid biosynthesis at the early infection stage of Verticillium longisporum in oilseed rape (Brassica napus).Molecular plant pathology · 2019Article
- A Simple Method for Measuring Apoplast Hydration and Collecting Apoplast Contents.Plant physiology · 2019Article
- Contribution of cell wall peroxidase- and NADPH oxidase-derived reactive oxygen species to Alternaria brassicicola-induced oxidative burst in Arabidopsis.Molecular plant pathology · 2019Article
- Plants strike back: Kiwellin proteins as a modular toolbox for plant defense mechanisms.Communicative & integrative biology · 2019Article
- Metabolic Profiling to Identify the Latent Infection of Strawberry byEvolutionary bioinformatics online · 2019Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Verticillium longisporum (VL) is one of the most devastating diseases in important oil crops from the family of Brassicaceae. The fungus resides for much time of its life cycle in the extracellular fluid of the vascular system, where it cannot be controlled by conventional fungicides. To obtain insights into the biology of VL-plant interaction in the apoplast, the secretome consisting of the extracellular proteome and metabolome as well as cell wall properties were studied in the model Brassicaceae, Arabidopsis thaliana. VL infection resulted in increased production of cell wall material with an altered composition of carbohydrate polymers and increased lignification. The abundance of several hundred soluble metabolites changed in the apoplast of VL-infected plants including signalling and defence compounds such as glycosides of salicylic acid, lignans and dihydroxybenzoic acid as well as oxylipins. The extracellular proteome of healthy leaves was enriched in antifungal proteins. VL caused specific increases in six apoplast proteins (three peroxidases PRX52, PRX34, P37, serine carboxypeptidase SCPL20, α-galactosidase AGAL2 and a germin-like protein GLP3), which have functions in defence and cell wall modification. The abundance of a lectin-like, chitin-inducible protein (CILLP) was reduced. Since the transcript levels of most of the induced proteins were not elevated until late infection time points (>20 dpi), whereas those of CILLP and GLP3 were reduced at earlier time points, our results may suggest that VL enhances its virulence by rapid down-regulation and delay of induction of plant defence genes.
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