ArticlePloS one2012
The gut fungus Basidiobolus ranarum has a large genome and different copy numbers of putatively functionally redundant elongation factor genes.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 22 citations in OpenAlex.
- Retroperitoneal Basidiobolomycosis Mimicking a Malignant Neoplasm.Gastroenterology research · 2026Article
- A rare case of invasive necrotizing myositis of the thigh caused byCurrent medical mycology · 2025Article
- Divergent Evolution of Early Terrestrial Fungi Reveals the Evolution of Mucormycosis Pathogenicity Factors.Genome biology and evolution · 2023Article
- The genus Entomophthora: bringing the insect destroyers into the twenty-first century.IMA fungus · 2021Review
- Bacterial-Like Nonribosomal Peptide Synthetases Produce Cyclopeptides in the Zygomycetous Fungus Mortierella alpina.Applied and environmental microbiology · 2021Article
- Fungal evolution: cellular, genomic and metabolic complexity.Biological reviews of the Cambridge Philosophical Society · 2020Article
- Dietary effects on gut microbiota of the mesquite lizard Sceloporus grammicus (Wiegmann, 1828) across different altitudes.Microbiome · 2020Article
- Skin and soft tissue infection caused byIDCases · 2020Article
- Fungal evolution: major ecological adaptations and evolutionary transitions.Biological reviews of the Cambridge Philosophical Society · 2019Review
- Human Pathogenic Entomophthorales.Clinical microbiology reviews · 2018Review
- Wood staining fungi revealed taxonomic novelties inStudies in mycology · 2016Article
- Human Fungal Pathogens of Mucorales and Entomophthorales.Cold Spring Harbor perspectives in medicine · 2014Review
- A complex distribution of elongation family GTPases EF1A and EFL in basal alveolate lineages.Genome biology and evolution · 2014Article
- An evolutionary ratchet leading to loss of elongation factors in eukaryotes.BMC evolutionary biology · 2014Article
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Authors and funding
2 authors at 1 institution in 1 country.
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Abstract
Fungal genomes range in size from 2.3 Mb for the microsporidian Encephalitozoon intestinalis up to 8000 Mb for Entomophaga aulicae, with a mean genome size of 37 Mb. Basidiobolus, a common inhabitant of vertebrate guts, is distantly related to all other fungi, and is unique in possessing both EF-1α and EFL genes. Using DNA sequencing and a quantitative PCR approach, we estimated a haploid genome size for Basidiobolus at 350 Mb. However, based on allelic variation, the nuclear genome is at least diploid, leading us to believe that the final genome size is at least 700 Mb. We also found that EFL was in three times the copy number of its putatively functionally overlapping paralog EF-1α. This suggests that gene or genome duplication may be an important feature of B. ranarum evolution, and also suggests that B. ranarum may have mechanisms in place that favor the preservation of functionally overlapping genes.
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