Evidence map›Paper›PMID 22363235›Full record

ArticleMarine drugs2011

Chitosan, the marine functional food, is a potent adsorbent of humic acid.

Jeen-Kuan Chen, Chao-Hsien Yeh, Lian-Chen Wang, Tzong-Horng Liou, Chia-Rui Shen, Chao-Lin Liu

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Diversity of family GH46 chitosanases in Kitasatospora setae KM-6054.Applied microbiology and biotechnology · 2017
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jeen-Kuan ChenEnvironment and Biotechnology Department, Refining and Manufacturing Research Institute, CPC Corporation, Chia-Yi 60051, Taiwan.
Chao-Hsien YehDepartment of Chemical Engineering, Ming Chi University of Technology, 84 Gung-Juan Road, Taishan, New Taipei 24301, Taiwan.
Lian-Chen WangDepartment of Parasitology, College of Medicine, Chang Gung University, 259 Wen-Hwa 1st Road, Kweishan, Tao-Yuan 24301, Taiwan.
Tzong-Horng LiouDepartment of Chemical Engineering, Ming Chi University of Technology, 84 Gung-Juan Road, Taishan, New Taipei 24301, Taiwan.
Chia-Rui ShenDepartment of Medical Biotechnology and Laboratory Science, Chang Gung University, 259 Wen-Hwa 1st Road, Kweishan, Tao-Yuan 33302, Taiwan.
Chao-Lin LiuDepartment of Chemical Engineering, Ming Chi University of Technology, 84 Gung-Juan Road, Taishan, New Taipei 24301, Taiwan.
Ming Chi University of Technology · TWChang Gung University · TWChina Petrochemical Development Corporation (Taiwan) · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chitosan is prepared by the deacetylation of chitin, the second-most abundant biopolymer in nature, and has applicability in the removal of dyes, heavy metals and radioactive waste for pollution control. In weight-reduction remedies, chitosan is used to form hydrogels with lipids and to depress the intestinal absorption of lipids. In this study, an experimental method was implemented to simulate the effect of chitosan on the adsorption of humic acid in the gastrointestinal tract. The adsorption capacity of chitosan was measured by its adsorption isotherm and analyzed using the Langmuir equation. The results showed that 3.3 grams of humic acid was absorbed by 1 gram of chitosan. The adsorption capacity of chitosan was much greater than that of chitin, diethylaminoethyl-cellulose or activated charcoal. Cellulose and carboxymethyl-cellulose, a cellulose derivative with a negative charge, could not adsorb humic acid in the gastrointestinal tract. This result suggests that chitosan entraps humic acid because of its positive charge.

Indexed as

Functional FoodHumic SubstancesAdsorptionChitosanHydrogen-Ion ConcentrationChitosanHumic SubstancesadsorbentBlackfootchitosanhumic acid

Identifiers

PMID22363235
PMCPMC3280574
OpenAlexW1982065344

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.