ArticleInternational journal of oral science2012
Investigation of basement membrane proteins in a case of granular cell ameloblastoma.
Article in International journal of oral science, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 15 citations in OpenAlex.
- Differentially expressed extracellular matrix genes functionally separate ameloblastoma from odontogenic keratocyst.BMC oral health · 2024Article
- Antigenic heterogeneity in granular cell ameloblastoma: an immunohistochemical study.Journal of international oral health : JIOH · 2015Article
- Massive granular cell ameloblastoma with dural extension and atypical morphology.Contemporary clinical dentistry · 2014Article
- Granular cell ameloblastoma of jaw - Report of a case with an emphasis on its characterization.Journal of clinical and experimental dentistry · 2013Article
- Rare giant granular cell ameloblastoma: a case report and an immunohistochemical study.Case reports in dentistry · 2013Article
- Granular cells in ameloblastoma: An enigma in diagnosis.Indian journal of dentistryArticle
- Ameloblastoma with distinctive granular cell pattern: an 8 case study.Autopsy & case reportsArticle
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Authors and funding
3 authors at 1 institution in 1 country.
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Abstract
Granular cell ameloblastoma is a rare, benign neoplasm of the odontogenic epithelium. A case of massive granular cell ameloblastoma in a 44-year-old Thai female is reported. Histopathological features displayed a follicular type of ameloblastoma with an accumulation of granular cells residing within the tumor follicles. After treatment by partial mandibulectomy, the patient showed a good prognosis without recurrence in a 2-year follow-up. To characterize the granular cells in ameloblastoma, we examined the expression of basement membrane (BM) proteins, including collagen type IV, laminins 1 and 5 and fibronectin using immunohistochemistry. Except for the granular cells, the tumor cells demonstrated a similar expression of BM proteins compared to follicular and plexiform ameloblastomas in our previous study, whereas the granular cells showed strong positivity to laminins 1 and 5 and fibronectin. The increased fibronectin expression in granular cells suggests a possibility of age-related transformation of granular cells in ameloblastoma.
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