Evidence map›Paper›PMID 2236037›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America1990

Electrophoretic karyotype for Dictyostelium discoideum.

E C Cox, C D Vocke, S Walter, K Y Gregg, E S Bain

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

E C CoxDepartment of Molecular Biology, Princeton University, NJ 08544-1003.
C D Vocke
S Walter
K Y Gregg
E S Bain

Funding

MOLECULAR CLONING OF DEVELOPMENTAL GENES OF SLIME MOLDSF32GM011730 · NIGMS · PRINCETON UNIVERSITY · PI VOCKE, CATHY D · 1987 to 1989
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GENETIC BASIS OF SPATIAL PATTERNINGR01HD023301 · NICHD · PRINCETON UNIVERSITY · PI COX, EDWARD C · 1988 to 1990
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NICHD NIH HHS HD23301NIGMS NIH HHS GM11730
6 · The paper itself

Abstract

This paper reports on the separation of the Dictyostelium discoideum chromosomes by pulse-field electrophoresis and the correlation of the electrophoretic pattern with linkage groups established by classical genetic methods. In two commonly used laboratory strains, five chromosome-sized DNA molecules have been identified. Although the majority of the molecular probes used in this study can be unambiguously assigned to established linkage groups, the electrophoretic karyotype differs between the closely related strains AX3k and NC4, suggesting that chromosomal fragmentation may have occurred during their maintenance and growth. The largest chromosome identified in this study is approximately 9 million base pairs. To achieve resolution with molecules of this size, programmed voltage gradients were used in addition to programmed pulse times.

Indexed as

Blotting, SouthernChromosomes, FungalDictyosteliumDNA, FungalDNA ProbesElectrophoresis, Agar GelKaryotypingDNA, FungalDNA Probes

Identifiers

PMID2236037
PMCPMC54932

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.