Evidence map›Paper›PMID 22360301›Full record

ArticleJournal of the American Chemical Society2012

Induction of pH sensitivity on the fluorescence lifetime of quantum dots by NIR fluorescent dyes.

Rui Tang, Hyeran Lee, Samuel Achilefu

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Cyanine dye-embedded fluorescent film for ratiometric pH measurement.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Article
  2. Chemical Regulation of Fluorescence Lifetime.Chemical & biomedical imaging · 2023
    Review
  3. Article
  4. Review
  5. Article
  6. NaNature communications · 2019
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rui TangDepartment of Radiology, Washington University, St. Louis, Missouri 63110, United States.
Hyeran Lee
Samuel Achilefu

Funding

Task Specific Project 3: Diffuse Optical TomographyU54CA136398 · NCI · WASHINGTON UNIVERSITY · PI WANG, LIHONG · 2008 to 2012
$6.0M
MOLECULAR PROBES AND METHODS FOR FLUORESCENCE LIFETIME TOMOGRAPHY AND MICROSCOPYR01EB008111 · NIBIB · WASHINGTON UNIVERSITY · PI ACHILEFU, SAMUEL · 2009 to 2012
$1.9M
NEAR INFRARED PH-SENSITIVE MOLECULAR PROBES FOR MICROSCOPY OF CELLS AND TISSUESR01EB007276 · NIBIB · WASHINGTON UNIVERSITY · PI ACHILEFU, SAMUEL · 2008 to 2011
$1.3M
Multiphoton microscopy using near infrared DyesR33CA123537 · NCI · WASHINGTON UNIVERSITY · PI ACHILEFU, SAMUEL · 2008 to 2010
$1.3M
NCI NIH HHS R33 CA123537NCI NIH HHS U54 CA136398NHLBI NIH HHS HHSN268201000046CNIBIB NIH HHS R01 EB007276NIBIB NIH HHS R01 EB008111
6 · The paper itself

Abstract

Modulation of the fluorescence lifetime (FLT) of CdTeSe/ZnS quantum dots (QDs) by near-IR (NIR) organic chromophores represents a new strategy for generating reproducible pH-sensing nanomaterials. The hybrid construct transfers the pH sensitivity of photolabile NIR cyanine dyes to highly emissive and long-lifetime pH-insensitive QDs, thereby inducing a reproducible FLT change from 29 ns at pH >7 to 12 ns at pH <5. This approach provides an unparalleled large dynamic FLT range for pH sensing at NIR wavelengths.

Indexed as

Hydrogen-Ion ConcentrationQuantum DotsFluorescenceFluorescence Resonance Energy TransferFluorescent DyesMicroscopy, Electron, TransmissionSpectrophotometry, UltravioletSpectroscopy, Near-InfraredFluorescent Dyes

Identifiers

PMID22360301
PMCPMC3303939

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.