ArticlePloS one2012
Dopamine modulates the rest period length without perturbation of its power law distribution in Drosophila melanogaster.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Article
- The Ins and Outs of Dopamine Transporter Gene Manipulation: In Vivo Models of DAT Dysfunction.Advances in neurobiology · 2025Review
- Article
- Alterations in biogenic amines levels associated with age-related muscular tissue impairment inSaudi journal of biological sciences · 2022Article
- Quantitative investigation reveals distinct phases in Drosophila sleep.Communications biology · 2021Article
- Movement patterns of the grey field slug (Deroceras reticulatum) in an arable field.Scientific reports · 2020Article
- Covert sleep-related biological processes are revealed by probabilistic analysis inProceedings of the National Academy of Sciences of the United States of America · 2020Article
- Serotonergic Modulation of Walking in Drosophila.Current biology : CB · 2019Article
- The clock components Period2, Cryptochrome1a, and Cryptochrome2a function in establishing light-dependent behavioral rhythms and/or total activity levels in zebrafish.Scientific reports · 2019Article
- Article
- Sweetness induces sleep through gustatory signalling independent of nutritional value in a starved fruit fly.Scientific reports · 2017Article
- A random acceleration model of individual animal movement allowing for diffusive, superdiffusive and superballistic regimes.Scientific reports · 2017Article
- Modulation of social space by dopamine inBiology letters · 2017Article
- The fractal organization of ultradian rhythms in avian behavior.Scientific reports · 2017Article
- A random walk description of individual animal movement accounting for periods of rest.Royal Society open science · 2016Article
- Goodness of fit to a mathematical model for Drosophila sleep behavior is reduced in hyposomnolent mutants.PeerJ · 2016Article
- Evidence for a pervasive 'idling-mode' activity template in flying and pedestrian insects.Royal Society open science · 2015Article
- Perturbations in dopamine synthesis lead to discrete physiological effects and impact oxidative stress response in Drosophila.Journal of insect physiology · 2015Article
- Article
- Scaling laws of ambush predator 'waiting' behaviour are tuned to a common ecology.Proceedings. Biological sciences · 2014Article
Corrections and comments
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4 authors.
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Abstract
We analyzed the effects of dopamine signaling on the temporal organization of rest and activity in Drosophila melanogaster. Locomotor behaviors were recorded using a video-monitoring system, and the amounts of movements were quantified by using an image processing program. We, first, confirmed that rest bout durations followed long-tailed (i.e., power-law) distributions, whereas activity bout durations did not with a strict method described by Clauset et al. We also studied the effects of circadian rhythm and ambient temperature on rest bouts and activity bouts. The fraction of activity significantly increased during subjective day and at high temperature, but the power-law exponent of the rest bout distribution was not affected. The reduction in rest was realized by reduction in long rest bouts. The distribution of activity bouts did not change drastically under the above mentioned conditions. We then assessed the effects of dopamine. The distribution of rest bouts became less long-tailed and the time spent in activity significantly increased after the augmentation of dopamine signaling. Administration of a dopamine biosynthesis inhibitor yielded the opposite effects. However, the distribution of activity bouts did not contribute to the changes. These results suggest that the modulation of locomotor behavior by dopamine is predominantly controlled by changing the duration of rest bouts, rather than the duration of activity bouts.
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