ArticlePloS one2012
Risk factors of household transmission of pandemic (H1N1) 2009 among patients treated with antivirals: a prospective study at a primary clinic in Japan.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Attack rates assessment of the 2009 pandemic H1N1 influenza A in children and their contacts: a systematic review and meta-analysis.PloS one · 2012Pooled it
- Comparative Effectiveness of Baloxavir Marboxil and Oseltamivir Treatment in Reducing Household Transmission of Influenza: A Post Hoc Analysis of the BLOCKSTONE Trial.Influenza and other respiratory viruses · 2024Trial
- Maternal Influenza Vaccination and the Risk of Laboratory-Confirmed Influenza Among Household Contacts Under the Age of Five in Mali.The American journal of tropical medicine and hygiene · 2019Trial
- Household Influenza Transmission and Healthcare Resource Utilization Among Patients Treated with Baloxavir vs Oseltamivir: A United States Outpatient Prospective Survey.Infectious diseases and therapy · 2024Article
- Influenza in Children and Adolescents: Epidemiology, Management, and Prevention.Pediatrics in review · 2023Article
- Reducing Influenza Virus Transmission: The Potential Value of Antiviral Treatment.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022Article
- Household transmission of influenza A and B within a prospective cohort during the 2013-2014 and 2014-2015 seasons.Statistics in medicine · 2021Article
- Healthcare Resource Use and Burden Associated with Influenza Transmission Among Household Members with a Primary Infection: Commercial Claims Data Analysis.ClinicoEconomics and outcomes research : CEOR · 2021Article
- Baloxavir treatment of ferrets infected with influenza A(H1N1)pdm09 virus reduces onward transmission.PLoS pathogens · 2020Article
- Efficacy of baloxavir marboxil on household transmission of influenza infection.Journal of pharmaceutical health care and sciences · 2020Article
- Household Transmission of Seasonal Influenza From HIV-Infected and HIV-Uninfected Individuals in South Africa, 2013-2014.The Journal of infectious diseases · 2019Article
- The effect of neuraminidase inhibitors on household transmission in Japanese patients with influenza A and B infection: A prospective, observational study.Influenza and other respiratory viruses · 2019Observational
- Influenza Transmission Dynamics in Urban Households, Managua, Nicaragua, 2012-2014.Emerging infectious diseases · 2018Article
- Household Transmission of Influenza Virus.Trends in microbiology · 2016Review
- Analysis of influenza transmission in the households of primary and junior high school students during the 2012-13 influenza season in Odate, Japan.BMC infectious diseases · 2015Article
- Factors associated with household transmission of pandemic (H1N1) 2009 among self-quarantined patients in Beijing, China.PloS one · 2013Article
- Influenza vaccination uptake among the working age population of Japan: results from a national cross-sectional survey.PloS one · 2013Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHousehold transmission of influenza can affect the daily lives of patients and their families and be a trigger for community transmission, thus it is necessary to take precautions to prevent household transmission. We aimed to determine the risks of household transmission of pandemic (H1N1) 2009 influenza virus from an index patient who visited a primary clinic and was treated with antiviral drugs.
methodsWe followed up all the patients who were diagnosed with influenza A by rapid diagnostic test with a questionnaire or interview from July 2009 to April 2010. Secondary cases were defined as patients visiting the clinic or other clinics and being positive for influenza A by rapid diagnostic test within 7 days of onset of an index patient. Logistic regression analysis was used to explore the association between household transmission and the studied variables.
resultsWe recruited 591 index patients and 1629 household contacts. The crude secondary attack rate was 7.3% [95% confidence interval (CI): 6.1-8.7]. Age of index patients (0-6 years old: odds ratio 2.56; 95% CI: 1.31-4.01; 7-12 years old: 2.44, 1.31-3.72; 30-39 years old 3.88; 2.09-5.21; 40 years old or more 2.76; 1.17-4.53) and number of household members with five or more (3.09, 2.11-4.07), medication started ≥48 hours from the onset of fever (2.38, 1.17-3.87) were significantly associated with household transmission.
conclusionsHousehold transmission was associated with index patients aged ≤12 years old and adults ≥30 years with children, with more than five persons in the household, and medication initiated ≥48 hours from the onset of fever among the population, in which, antiviral treatment was given to all patients. We need to warn patients at high risk of household transmission to take additional precautions.
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