ArticleCytotechnology1995
The prophylactic use of antibiotics in cell culture.
Article in Cytotechnology, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Improve your success with fish cell lines-small things that matter.In vitro cellular & developmental biology. Animal · 2026Review
- Application of Human Plasma/Serum to Cell Culture In Vitro: A Translational Research Approach to Better Define Disease Mechanisms.Clinical and translational science · 2025Review
- Interactions of SARS-CoV-2 with Human Target Cells-A Metabolic View.International journal of molecular sciences · 2024Review
- Penicillin in Borrelia burgdorferi-negative Primary Cutaneous Marginal Zone Lymphoma: A Case Series and Literature Review.Acta dermato-venereologica · 2022Review
- Medicated Scaffolds Prepared with Hydroxyapatite/Streptomycin Nanoparticles Encapsulated into Polylactide Microfibers.International journal of molecular sciences · 2022Article
- Cryopreservation in 95% serum with 5% DMSO maintains colony formation and chondrogenic abilities in human synovial mesenchymal stem cells.BMC musculoskeletal disorders · 2019Article
- Creating tissue on chip constructs in microtitre plates for drug discovery.RSC advances · 2018Article
- A urine-dependent human urothelial organoid offers a potential alternative to rodent models of infection.Scientific reports · 2018Article
- 3 dimensional cell cultures: a comparison between manually and automatically produced alginate beads.Cytotechnology · 2016Article
- Isolation of CD 90+ Fibroblast/Myofibroblasts from Human Frozen Gastrointestinal Specimens.Journal of visualized experiments : JoVE · 2016Article
- Characterisation of seven newly established head and neck squamous cell carcinoma cell lines.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2015Article
- MMP-2 mediates local degradation and remodeling of collagen by annulus fibrosus cells of the intervertebral disc.Arthritis research & therapy · 2013Article
- Developmental incompatibility of human parthenogenetic embryonic stem cells in mouse blastocysts.In vitro cellular & developmental biology. Animal · 2012Article
- Prevention and detection of Mycoplasma contamination in cell culture.Cell journal · 2012Article
- Antibiotic-induced change of bacterial communities associated with the copepod Nitocra spinipes.PloS one · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This article describes the historical development of the prophylactic use of antibiotics in cell culture as well as their effects on cells. The influence of antibiotics on cell morphology, cellular degeneration and cell death and cellular function is summarized. Cellular DNA as well as protein synthesis are affected which can lead to interference with, or even changes in, metabolic processes. Such effects must be considered in cell culture research. As antibiotics are used in multifold ways, the otherwise standardized conditions in cell culture are no longer comparable. The prophylactic use of antibiotics is rejected for scientific reasons.
Identifiers
22359010What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.