ArticleThe Journal of organic chemistry2012
Synthesis of pyrido[1,2-a]indole malonates and amines through aryne annulation.
Article in The Journal of organic chemistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Rearrangement Cascade Initiated by Nucleophilic Benzyne Attack on 3,6-Di(2-pyridyl)-1,2-diazines.ACS organic & inorganic Au · 2025Article
- Primary Pyrrolimines and Pyridinimines.Molecules (Basel, Switzerland) · 2025Article
- Palladium(II)-catalyzed annulation of N-methoxy amides and arynes: computational mechanistic insights and substituents effects.Journal of molecular modeling · 2024Article
- Enantioselective synthesis of α-tetrasubstituted (1-indolizinyl) (diaryl)-methanaminesRSC advances · 2024Article
- Enantioselective synthesis of α-tetrasubstituted (3-indolizinyl) (diaryl)methanaminesRSC advances · 2022Article
- A pyrone remodeling strategy to access diverse heterocycles: application to the synthesis of fascaplysin natural products.Chemical science · 2020Article
- Denitrogenative Transformations of Pyridotriazoles and Related Compounds: Synthesis ofThe Journal of organic chemistry · 2020Article
- Intermolecular C-O Addition of Carboxylic Acids to Arynes: Synthesis ofTetrahedron · 2013Article
- Synthesis of o-(dimethylamino)aryl ketones, acridones, acridinium salts, and 1H-indazoles by the reaction of hydrazones and arynes.The Journal of organic chemistry · 2012Article
- Palladium-catalyzed annulation of arynes by o-halobenzamides: synthesis of phenanthridinones.The Journal of organic chemistry · 2012Article
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Authors and funding
4 authors.
Funding
Abstract
Pyrido[1,2-a]indoles are known as medicinally and pharmaceutically important compounds, but there is a lack of efficient methods for their synthesis. We report a convenient and efficient route to these privileged structures starting from easily accessible 2-substituted pyridines and aryne precursors. A small library of compounds has been synthesized utilizing the developed method, affording variously substituted pyrido[1,2-a]indoles in moderate to good yields.
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