Evidence map›Paper›PMID 22356329›Full record

ArticleThe New England journal of medicine2012

Realizing genomic medicine.

Elizabeth G Phimister, W Gregory Feero, Alan E Guttmacher

Registry-linked trialAbstract readEditorialComment
PubMed Publisher
In one paragraph

Article in The New England journal of medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02625155 (Standard of Care Versus Urine Testing With Selective PHarmacogenomics for Effective Drug and Dosing REgimens), which is not on this map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02625155 phase4unknown statusnot on this mapstarted 2015, after this paper: background citation

Standard of Care Versus Urine Testing With Selective PHarmacogenomics for Effective Drug and Dosing REgimens: SPHERE

TypeinterventionalSponsorInSource DiagnosticsRan2015Enrolled14,000ConditionsTarget Drug-related Adverse EventsArmsUrine diagnostic testing as SOC, drug regimen changes per SOC, Urine diagnostic testing with selective PGx testing, drug regimen changes based on PGx test results
3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Navigating the research-clinical interface in genomic medicine: analysis from the CSER Consortium.Genetics in medicine : official journal of the American College of Medical Genetics · 2018
    Article
  3. Review
  4. Review
  5. Article
  6. Neurogenomics: An Egyptian perspective.Applied & translational genomics · 2015
    Article
  7. Review
  8. Mapping the Ethics of Translational Genomics: Situating Return of Results and Navigating the Research-Clinical Divide.The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics · 2015
    Article
  9. Article
  10. Whole-genome sequencing and the clinician: a tale of two cities.Journal of neurology, neurosurgery, and psychiatry · 2014
    Article
  11. Genomic counseling: next generation counseling.Journal of genetic counseling · 2014
    Article
  12. Article
  13. Personalized medicine in hematology - A landmark from bench to bed.Computational and structural biotechnology journal · 2014
    Review
  14. Article
  15. Review
  16. Relevance of genomics to healthcare and nursing practice.Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing · 2013
    Article
  17. Article
  18. Survey of nursing integration of genomics into nursing practice.Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing · 2012
    Article
  19. Review
  20. How genetic variant libraries effectively extend gene testing patents: implications for intellectual property and good clinical care.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2012
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Elizabeth G Phimister
W Gregory Feero
Alan E Guttmacher

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Chromosome AberrationsMutationChild Development Disorders, PervasiveHumansIntellectual DisabilitySequence Analysis, DNA

Identifiers

PMID22356329

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.