ArticleScientific reports2011
Defining the tipping point: a complex cellular life/death balance in corals in response to stress.
Article in Scientific reports, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 47 citations in OpenAlex.
- Transcriptional responses of reef-building coral Leptoria phrygia to localized thermal anomalies: a seasonal and experimental approach.Scientific reports · 2026Article
- Metaproteome Analysis of Short-Term Thermal Stress in Three Sympatric Coral Species Reveals Divergent Host Responses.Ecology and evolution · 2026Article
- Comparative Proteomic Analysis of Non-Bleached and Bleached Fragments of the HydrocoralBiology · 2025Article
- Predictive models for the selection of thermally tolerant corals based on offspring survival.Nature communications · 2022Article
- AnFrontiers in bioengineering and biotechnology · 2022Article
- Bioactivity Potential of Marine Natural Products from Scleractinia-Associated Microbes and In Silico Anti-SARS-COV-2 Evaluation.Marine drugs · 2020Review
- Article
- The regulation of thermal stress induced apoptosis in corals reveals high similarities in gene expression and function to higher animals.Scientific reports · 2016Article
- Breakdown of coral colonial form under reduced pH conditions is initiated in polyps and mediated through apoptosis.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- The Chondroprotective Role of TMF in PGE2-Induced Apoptosis Associating with Endoplasmic Reticulum Stress.Evidence-based complementary and alternative medicine : eCAM · 2015Article
- Host Coenzyme Q Redox State Is an Early Biomarker of Thermal Stress in the Coral Acropora millepora.PloS one · 2015Article
- Extensive differences in gene expression between symbiotic and aposymbiotic cnidarians.G3 (Bethesda, Md.) · 2014Article
- Microbes in the coral holobiont: partners through evolution, development, and ecological interactions.Frontiers in cellular and infection microbiology · 2014Review
- KEGG orthology-based annotation of the predicted proteome of Acropora digitifera: ZoophyteBase - an open access and searchable database of a coral genome.BMC genomics · 2013Article
- Genomic basis for coral resilience to climate change.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Apoptotic cell death has been implicated in coral bleaching but the molecules involved and the mechanisms by which apoptosis is regulated are only now being identified. In contrast the mechanisms underlying apoptosis in higher animals are relatively well understood. To better understand the response of corals to thermal stress, the expression of coral homologs of six key regulators of apoptosis was studied in Acropora aspera under conditions simulating those of a mass bleaching event. Significant changes in expression were detected between the daily minimum and maximum temperatures. Maximum daily temperatures from as low as 3°C below the bleaching threshold resulted in significant changes in both pro- and anti-apoptotic gene expression. The results suggest that the control of apoptosis is highly complex in this eukaryote-eukaryote endosymbiosis and that apoptotic cell death cascades potentially play key roles tipping the cellular life/death balance during environmental stress prior to the onset of coral bleaching.
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Registered trials
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