ArticleRare tumors2011
Successful radiotherapy for local control of progressively increasing metastasis of gastrointestinal stromal tumor.
Article in Rare tumors, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 23 citations in OpenAlex.
- Soft Tissue Sarcomas: Treatment and Management.Cancers · 2024Article
- Clinical characteristics and prognosis of gastrointestinal stromal tumors with rare site metastasis (Review).Oncology letters · 2022Review
- Radiotherapy in the Management of Gastrointestinal Stromal Tumors: A Systematic Review.Cancers · 2022Review
- Article
- Simultaneous Integrated Boost Intensity-Modulated Radiotherapy for Locally Advanced Drug-Resistant Gastrointestinal Stromal Tumors: A Feasibility Study.Frontiers in oncology · 2020Article
- A Rare Case of a Metastatic Gastrointestinal Stromal Tumor (GIST): a Case Report and Review of the Literature.Journal of gastrointestinal cancer · 2019Review
- Radiotherapy for Gastrointestinal Stromal Tumors.Chinese medical journal · 2018Review
- Radiotherapy in the management of gist: state of the art and new potential scenarios.Clinical sarcoma research · 2017Article
- Article
- Considering the role of radiation therapy for gastrointestinal stromal tumor.OncoTargets and therapy · 2014Article
- External beam radiation therapy for locally advanced and metastatic gastrointestinal stromal tumors.Radiation oncology (London, England) · 2013Article
- Gastrointestinal Stromal Tumour with Synchronous Bone Metastases: A Case Report and Literature Review.Case reports in oncologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gastrointestinal stromal tumors (GISTs) are known to be poorly responsive to conventional chemotherapy and historically considered resistant to radiotherapy. In the past the mainstay of GIST treatment was surgery, but the introduction of tyrosine kinase inhibitors (TKIs) imatinib and sunitinib marked the beginning of a new era in the treatment of GIST patients. To date, radiotherapy for GIST has not been administered in clinical practice except for limited palliative settings and there are no clear data on the administration of radiotherapy, alone or in combination with TKIs, with a purely cytoreductive intent. We describe the clinical case of a 48-year-old woman with metastatic GIST treated with external radiotherapy in a critical supraclavicular tumor localization progressively increasing in size with several symptoms and not responsive to systemic TKI therapies. We obtained an initial shrinkage of the mass and subsequent stabilization with an immediate and clear clinical benefit. Although the historical medical literature considered GISTs resistant to radiation therapy, our clinical case suggests this treatment may be appropriate in selected patients.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.