ReviewViruses2012
Immunity to fish rhabdoviruses.
Review in Viruses, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 107 citations in OpenAlex.
- Review
- Overcoming Target Drift: Development and Validation of a One-Step TaqMan qPCR Assay for Epidemiological Surveillance ofMicroorganisms · 2026Article
- First Report of Snakehead Rhabdovirus-Like Novirhabdovirus Associated With Acute Mortality in Multiple Outbreaks in Farmed Giant Snakehead (Channa micropeltes) in Thailand.Transboundary and emerging diseases · 2026Article
- Efficacy of a Combined Natural Extract of Turmeric (Curcuma longa) and Liquorice (Glycyrrhiza uralensis) Against Viral Haemorrhagic Septicaemia Virus in Olive Flounders (Paralichthys olivaceus).Journal of fish diseases · 2026Article
- Integrated Enzyme-Mediated One-Step Sample Processing and Duplex Amplification System for Rapid Detection ofFoods (Basel, Switzerland) · 2025Article
- One-step and two-step qPCR assays for CAPRV2023: development and application in full-cycle epidemiological surveillance of golden pompano.Frontiers in veterinary science · 2025Article
- MiR-130c-5p targets the SHVVFrontiers in immunology · 2024Article
- Pathogenic Mechanism of a Highly Virulent Infectious Hematopoietic Necrosis Virus in Head Kidney of Rainbow Trout (Viruses · 2022Article
- Integrated analysis of immune parameters, miRNA-mRNA interaction, and immune genes expression in the liver of rainbow trout following infectious hematopoietic necrosis virus infection.Frontiers in immunology · 2022Article
- Immunological Effects of RecombinantFrontiers in immunology · 2022Article
- α-Lipoic Acid Exerts Its Antiviral Effect against Viral Hemorrhagic Septicemia Virus (VHSV) by Promoting Upregulation of Antiviral Genes and Suppressing VHSV-Induced Oxidative Stress.Virologica Sinica · 2021Article
- Chitosan Treatment of E-11 Cells Modulates Transcription of Nonspecific Immune Genes and Reduces Nodavirus Capsid Protein Gene Expression.Animals : an open access journal from MDPI · 2021Article
- Temperature Variation and Host Immunity Regulate Viral Persistence in a Salmonid Host.Pathogens (Basel, Switzerland) · 2021Article
- Article
- Transcriptome profiling in head kidney of rainbow trout (Oncorhynchus mykiss) after infection with the low-virulent Nagano genotype of infectious hematopoietic necrosis virus.Archives of virology · 2021Article
- HSC70 Inhibits Spring Viremia of Carp Virus Replication by Inducing MARCH8-Mediated Lysosomal Degradation of G Protein.Frontiers in immunology · 2021Article
- Naturally occurring substitution in one amino acid in VHSV phosphoprotein enhances viral virulence in flounder.PLoS pathogens · 2021Article
- Natural killer cell responses to emerging viruses of zoonotic origin.Current opinion in virology · 2020Review
- Grass Carp Reovirus (GCRV) Giving Its All to Suppress IFN Production by Countering MAVS Signaling Transduction.Frontiers in immunology · 2020Article
- Transcriptome analysis based on RNA-seq of common innate immune responses of flounder cells to IHNV, VHSV, and HIRRV.PloS one · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Members of the family Rhabdoviridae are single-stranded RNA viruses and globally important pathogens of wild and cultured fish and thus relatively well studied in their respective hosts or other model systems. Here, we review the protective immune mechanisms that fish mount in response to rhabdovirus infections. Teleost fish possess the principal components of innate and adaptive immunity found in other vertebrates. Neutralizing antibodies are critical for long-term protection from fish rhabdoviruses, but several studies also indicate a role for cell-mediated immunity. Survival of acute rhabdoviral infection is also dependent on innate immunity, particularly the interferon (IFN) system that is rapidly induced in response to infection. Paradoxically, rhabdoviruses are sensitive to the effects of IFN but virulent rhabdoviruses can continue to replicate owing to the abilities of the matrix (M) protein to mediate host-cell shutoff and the non‑virion (NV) protein to subvert programmed cell death and suppress functional IFN. While many basic features of the fish immune response to rhabdovirus infections are becoming better understood, much less is known about how factors in the environment affect the ecology of rhabdovirus infections in natural populations of aquatic animals.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.