Evidence map›Paper›PMID 22355451›Full record

ArticleViruses2012

Analysis of the genome of the sexually transmitted insect virus Helicoverpa zea nudivirus 2.

John P Burand, Woojin Kim, Claudio L Afonso, Edan R Tulman, Gerald F Kutish, Zhiqiang Lu, Daniel L Rock

Open access · goldAbstract readComparative Study
In one paragraph

Article in Viruses, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Nudivirus Remnants in the Genomes of Arthropods.Genome biology and evolution · 2020
    Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

John P BurandDepartment of Plant, Soil and Insect Sciences, University of Massachusetts Amherst, Amherst, MA 01003, USA. jburand@microbio.umass.edu
Woojin Kim
Claudio L Afonso
Edan R Tulman
Gerald F Kutish
Zhiqiang Lu
Daniel L Rock
Plum Island Animal Disease Center · USUniversity of Massachusetts Amherst · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The sexually transmitted insect virus Helicoverpa zea nudivirus 2 (HzNV-2) was determined to have a circular double-stranded DNA genome of 231,621 bp coding for an estimated 113 open reading frames (ORFs). HzNV-2 is most closely related to the nudiviruses, a sister group of the insect baculoviruses. Several putative ORFs that share homology with the baculovirus core genes were identified in the viral genome. However, HzNV-2 lacks several key genetic features of baculoviruses including the late transcriptional regulation factor, LEF-1 and the palindromic hrs, which serve as origins of replication. The HzNV-2 genome was found to code for three ORFs that had significant sequence homology to cellular genes which are not generally found in viral genomes. These included a presumed juvenile hormone esterase gene, a gene coding for a putative zinc-dependent matrix metalloprotease, and a major facilitator superfamily protein gene; all of which are believed to play a role in the cellular proliferation and the tissue hypertrophy observed in the malformation of reproductive organs observed in HzNV-2 infected corn earworm moths, Helicoverpa zea.

Indexed as

Genome, ViralAmino Acid SequenceAnimalsBaculoviridaeBase SequenceBiological EvolutionConsensus SequenceDNA VirusesFemaleInsect VirusesMolecular Sequence DataMothsOpen Reading FramesPhylogenySequence AlignmentSequence HomologyViral Proteinsbaculoviruscorn earwormHelicoverpa zeaHzNV-1HzNV-2juvenile hormone esterasenudivirussexually transmitted virussterile insectsvirus genome

Identifiers

PMID22355451
PMCPMC3280521
OpenAlexW2081538815

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.