ArticlePloS one2012
Genome-wide identification and analysis of grape aldehyde dehydrogenase (ALDH) gene superfamily.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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66 citing papers in PubMed, 112 citations in OpenAlex.
- Integrative expression profiling and comparative bioinformatics analysis of ALDH7A1 in chickpea (Cicer arietinum L.) under salt and ABA treatments.BMC plant biology · 2026Article
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- Genome-wide analysis of the ALDH superfamily inFrontiers in plant science · 2026Article
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- Genomic and Multi-Omics Analysis ofJournal of fungi (Basel, Switzerland) · 2025Article
- Identification of Aldehyde Dehydrogenase Gene Family inInternational journal of molecular sciences · 2025Article
- Genome-Wide Identification and Expression Analysis of the Melon Aldehyde Dehydrogenase (ALDH) Gene Family in Response to Abiotic and Biotic Stresses.Plants (Basel, Switzerland) · 2024Article
- NAC61 regulates late- and post-ripening osmotic, oxidative, and biotic stress responses in grapevine.Journal of experimental botany · 2024Article
- Genome-wide identification and expression analysis of the ALDH gene family and functional analysis ofPhysiology and molecular biology of plants : an international journal of functional plant biology · 2024Article
- Comprehensive analysis of the aldehyde dehydrogenase gene family inFrontiers in plant science · 2024Article
- Functional Characterization of Aldehyde Dehydrogenase inMicroorganisms · 2023Article
- Genome-wide identification and expression analysis of PtJAZ gene family in poplar (Populus trichocarpa).BMC genomic data · 2023Article
- Genome-wide characterization of aldehyde dehydrogenase gene family members in groundnut (Frontiers in plant science · 2023Article
- Article
- Aldehyde dehydrogenase superfamily in sorghum: genome-wide identification, evolution, and transcript profiling during development stages and stress conditions.BMC plant biology · 2022Article
- Comparative genomic analysis of the aldehyde dehydrogenase gene superfamily inFrontiers in plant science · 2022Article
- Review
- Aldehyde Dehydrogenase 3 Is an Expanded Gene Family with Potential Adaptive Roles in Chickpea.Plants (Basel, Switzerland) · 2021Article
- Genome-wide identification, evolution, and transcript profiling of Aldehyde dehydrogenase superfamily in potato during development stages and stress conditions.Scientific reports · 2021Article
6 more citing papers are in PubMed but not listed here.
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundThe completion of the grape genome sequencing project has paved the way for novel gene discovery and functional analysis. Aldehyde dehydrogenases (ALDHs) comprise a gene superfamily encoding NAD(P)(+)-dependent enzymes that catalyze the irreversible oxidation of a wide range of endogenous and exogenous aromatic and aliphatic aldehydes. Although ALDHs have been systematically investigated in several plant species including Arabidopsis and rice, our knowledge concerning the ALDH genes, their evolutionary relationship and expression patterns in grape has been limited. METHODOLOGY/PRINCIPAL
findingsA total of 23 ALDH genes were identified in the grape genome and grouped into ten families according to the unified nomenclature system developed by the ALDH Gene Nomenclature Committee (AGNC). Members within the same grape ALDH families possess nearly identical exon-intron structures. Evolutionary analysis indicates that both segmental and tandem duplication events have contributed significantly to the expansion of grape ALDH genes. Phylogenetic analysis of ALDH protein sequences from seven plant species indicates that grape ALDHs are more closely related to those of Arabidopsis. In addition, synteny analysis between grape and Arabidopsis shows that homologs of a number of grape ALDHs are found in the corresponding syntenic blocks of Arabidopsis, suggesting that these genes arose before the speciation of the grape and Arabidopsis. Microarray gene expression analysis revealed large number of grape ALDH genes responsive to drought or salt stress. Furthermore, we found a number of ALDH genes showed significantly changed expressions in responses to infection with different pathogens and during grape berry development, suggesting novel roles of ALDH genes in plant-pathogen interactions and berry development.
conclusionThe genome-wide identification, evolutionary and expression analysis of grape ALDH genes should facilitate research in this gene family and provide new insights regarding their evolution history and functional roles in plant stress tolerance.
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