Evidence map›Paper›PMID 22354822›Full record

ArticleEndoscopy2012

Submucosal endoscopic tumor resection for subepithelial tumors in the esophagus and cardia.

H Inoue, H Ikeda, T Hosoya, M Onimaru, A Yoshida, N Eleftheriadis, R Maselli, S Kudo

Abstract read
PubMed Publisher
In one paragraph

Article in Endoscopy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 118 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
118citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

118 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Endoscopic resection of gastric submucosal tumors: A comparison of endoscopic nontunneling with tunneling resection and a systematic review.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Pooled it
  4. Bladder pressure monitoring and COJournal of clinical monitoring and computing · 2018
    Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Peroral endoscopic tumor resection of recurrent hypopharyngeal fibrovascular polyp.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2025
    Review
  14. Article
  15. Recent Advances in Endoscopic Treatment Techniques for Subepithelial Lesions.The Korean journal of helicobacter and upper gastrointestinal research · 2025
    Review
  16. Article
  17. Article
  18. Article
  19. [Management of Colorectal Subepithelial Lesions: Differential Diagnosis and Follow-up].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2025
    Review
  20. Review

58 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

H InoueDigestive Disease Center, Showa University Northern Yokohama Hospital, Yokohama, Japan. haruinoue777@yahoo.co.jp
H Ikeda
T Hosoya
M Onimaru
A Yoshida
N Eleftheriadis
R Maselli
S Kudo

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND STUDY

aimsResection of submucosal tumors by means of endoscopy has been reported using a variety of techniques, but cannot be performed safely in tumors originating from the muscularis propria. Using the submucosal tunnel created by the technique of peroral endoscopic myotomy (POEM), we report the first series describing the new technique of submucosal endoscopic tumor resection (SET) for tumors of the esophagus and cardia. PATIENTS AND

methodsSET was attempted in nine consecutive patients with tumors (size >2cm) of either the esophagus or cardia with clinical indications for lesion removal. Following creation of a submucosal tunnel from 5 cm above the tumor, as described previously, the tumor was dissected from the overlying mucosa/submucosa and then carefully removed from the muscular layer using triangle-tip and insulated-tip knives. Following specimen retrieval through the tunnel, the orifice was closed by clips.

resultsOf the nine patients, two had tumors that were too large (60 mm and 75 mm, respectively) to allow safe removal due to loss of endoscopic overview. All remaining tumors (maximal tumor extension 12-30 mm) could be resected safely using this method. No complications occurred and follow-up was unremarkable. On histology, all tumors were resected completely (one gastrointestinal stromal tumor, five leiomyomas). The technique had to be modified in one patient with an aberrant pancreas.

conclusionsSET is a promising new technique for selected submucosal tumors in the esophagus and cardia up to a size of 4 cm and should be studied further.

Indexed as

AdultAgedCardiaEsophageal NeoplasmsEsophagoscopyFemaleGastric MucosaGastrointestinal Stromal TumorsGastroscopyHumansLeiomyomaMaleMiddle AgedStomach Neoplasms

Identifiers

PMID22354822

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.