Evidence map›Paper›PMID 22354500›Full record

ArticleIntensive care medicine2012

Development of demographics and outcome of very old critically ill patients admitted to intensive care units.

Gerald C Ihra, Judith Lehberger, Helene Hochrieser, Peter Bauer, Rene Schmutz, Barbara Metnitz, Philipp G H Metnitz

Abstract readComparative StudyMulticenter Study
PubMed Publisher
In one paragraph

Article in Intensive care medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 4 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. [Frailty in intensive care medicine].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gerald C IhraDepartment of Anesthesiology and General Intensive Care, Medical University of Vienna, Vienna, Austria. gerald.ihra@meduniwien.ac.at
Judith Lehberger
Helene Hochrieser
Peter Bauer
Rene Schmutz
Barbara Metnitz
Philipp G H Metnitz

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the development of demographics and outcome of very old (>80 years) critically ill patients admitted to intensive care units.

settingAll consecutive patients admitted to 41 Austrian intensive care units (ICUs) over an 11-year period.

methodsWe performed a retrospective cohort study of prospectively collected data. To compare parameters over time, patients were divided into three groups (group I from 1998 until 2001, group II from 2002 to 2004, and group III from 2005 to 2008).

resultsA total of 17,126 patients older than 80 years of age were admitted over the study period. The proportion of very old patients increased from 11.5% (I) to 15.3% (III) with a significant higher prevalence of females in all groups (on average 63.2%). Severity of illness also increased over time, even when corrected for age. Use of noninvasive mechanical ventilation increased over the years. However, risk-adjusted mortality rates [observed-to-expected (O/E) ratios] decreased from 1.14 [confidence interval (CI) 1.11-1.18] to 1.02 (CI 0.99-1.05). This improvement in outcome was confirmed on multivariate analysis: for every year delay in ICU admission, the odds to die decreased by 3%. Moreover, females exhibited a better outcome compared with males.

conclusionsThe relative and absolute numbers of very old patients increased over the study period, as did the severity of illness. Despite this, risk-adjusted hospital mortality improved over the study period. Females dominated in the very old patients and exhibited moreover a better outcome compared with males.

Indexed as

Critical IllnessIntensive Care UnitsOutcome Assessment, Health CareAdultAgedAged, 80 and overAge FactorsAustriaChi-Square DistributionDemographyFemaleHospital MortalityHumansLogistic ModelsMaleMiddle Aged

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.