ArticleHeredity2012
Early evolutionary colocalization of the nuclear ribosomal 5S and 45S gene families in seed plants: evidence from the living fossil gymnosperm Ginkgo biloba.
Article in Heredity, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 44 citations in OpenAlex.
- Genome architecture modulates 35S and 5S rDNA homogenization in Asteraceae.The Plant journal : for cell and molecular biology · 2026Article
- Review
- Comparative cytogenomic characterization of 18 wheat core collection cultivars from six continents using triple-color PLOP-FISH.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Intragenomic rDNA variation - the product of concerted evolution, mutation, or something in between?Heredity · 2023Review
- Analysis of 5S rDNA Genomic Organization Through the RepeatExplorer2 Pipeline: A Simplified Protocol.Methods in molecular biology (Clifton, N.J.) · 2023Article
- The Use of Ribosomal DNA for Comparative Cytogenetics.Methods in molecular biology (Clifton, N.J.) · 2023Article
- The Divergence of Chromosome Structures and 45S Ribosomal DNA Organization inPlants (Basel, Switzerland) · 2022Article
- Genome structure and diversity among Cynanchum wilfordii accessions.BMC plant biology · 2022Article
- The Nuclear 35S rDNA World in Plant Systematics and Evolution: A Primer of Cautions and Common Misconceptions in Cytogenetic Studies.Frontiers in plant science · 2022Review
- Personal Perspectives on Plant Ribosomal RNA Genes Research: From Precursor-rRNA to Molecular Evolution.Frontiers in plant science · 2021Review
- Comparative Chromosomal Localization of 45S and 5S rDNA Sites in 76 Purple-Fleshed Sweet Potato Cultivars.Plants (Basel, Switzerland) · 2020Article
- Cytogenetic analysis of Bienertia sinuspersici Akhani as the first step in genome sequencing.Genes & genomics · 2020Article
- In silico mining and FISH mapping of a chromosome-specific satellite DNA in Capsicum annuum L.Genes & genomics · 2019Article
- Pre-labelled oligo probe-FISH karyotype analyses of four Araliaceae species using rDNA and telomeric repeat.Genes & genomics · 2019Article
- Remarkable variation of ribosomal DNA organization and copy number in gnetophytes, a distinct lineage of gymnosperms.Annals of botany · 2019Article
- Rapid and Efficient FISH using Pre-Labeled Oligomer Probes.Scientific reports · 2018Article
- A Highly Dense Genetic Map forFrontiers in plant science · 2017Article
- A Portrait of Ribosomal DNA Contacts with Hi-C Reveals 5S and 45S rDNA Anchoring Points in the Folded Human Genome.Genome biology and evolution · 2016Article
- Article
- Complete chloroplast and ribosomal sequences for 30 accessions elucidate evolution of Oryza AA genome species.Scientific reports · 2015Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In seed plants, the colocalization of the 5S loci within the intergenic spacer (IGS) of the nuclear 45S tandem units is restricted to the phylogenetically derived Asteraceae family. However, fluorescent in situ hybridization (FISH) colocalization of both multigene families has also been observed in other unrelated seed plant lineages. Previous work has identified colocalization of 45S and 5S loci in Ginkgo biloba using FISH, but these observations have not been confirmed recently by sequencing a 1.8 kb IGS. In this work, we report the presence of the 45S-5S linkage in G. biloba, suggesting that in seed plants the molecular events leading to the restructuring of the ribosomal loci are much older than estimated previously. We obtained a 6.0 kb IGS fragment showing structural features of functional sequences, and a single copy of the 5S gene was inserted in the same direction of transcription as the ribosomal RNA genes. We also obtained a 1.8 kb IGS that was a truncate variant of the 6.0 kb IGS lacking the 5S gene. Several lines of evidence strongly suggest that the 1.8 kb variants are pseudogenes that are present exclusively on the satellite chromosomes bearing the 45S-5S genes. The presence of ribosomal IGS pseudogenes best reconciles contradictory results concerning the presence or absence of the 45S-5S linkage in Ginkgo. Our finding that both ribosomal gene families have been unified to a single 45S-5S unit in Ginkgo indicates that an accurate reassessment of the organization of rDNA genes in basal seed plants is necessary.
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