ArticleAnnals of intensive care2012
Results of noninvasive ventilation in very old patients.
Article in Annals of intensive care, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Do-not-intubate orders in patients with acute respiratory failure: a systematic review and meta-analysis.Intensive care medicine · 2020Pooled it
- Clinical Characteristics and Outcomes of Non-Invasive Ventilation Following Unplanned Extubation in the Elderly ICU Patients: A Retrospective Cohort Study.Clinical interventions in aging · 2026Article
- Role of Non-Invasive Ventilation in Elderly Patients: Therapeutic Opportunity or Medical Futility? An Updated Narrative Review.Medicina (Kaunas, Lithuania) · 2025Review
- Highlights from the Respiratory Failure and Mechanical Ventilation 2022 Conference.ERJ open research · 2023Article
- Article
- Clinical Outcomes in Patients Aged 80 Years or Older Receiving Non-Invasive Respiratory Support for Hypoxemic Acute Respiratory Failure Consequent to COVID-19.Journal of clinical medicine · 2022Article
- Noninvasive ventilation in critically ill very old patients with pneumonia: A multicenter retrospective cohort study.PloS one · 2021Article
- Don't forget shared decision-making in the COVID-19 crisis.Internal medicine journal · 2020Article
- Cumulative Prognostic Score Predicting Mortality in Patients Older Than 80 Years Admitted to the ICU.Journal of the American Geriatrics Society · 2019Article
- Non-invasive ventilation for acute hypercapnic respiratory failure in older patients.Wiener klinische Wochenschrift · 2017Article
- The Role of Noninvasive Ventilation in Patients with "Do Not Intubate" Order in the Emergency Setting.PloS one · 2016Article
- Is non-invasive ventilation the best ventilatory support for 'do not intubate' patients?Critical care (London, England) · 2012Article
- Noninvasive mechanical ventilation for very old patients with limitations of care: is the ICU the most appropriate setting?Critical care (London, England) · 2012Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNoninvasive ventilation (NIV) is frequently used for the management of acute respiratory failure (ARF) in very old patients (≥ 80 years), often in the context of a do-not-intubate order (DNI). We aimed to determine its efficacy and long-term outcome.
methodsProspective cohort of all patients admitted to the medical ICU of a tertiary hospital during a 2-year period and managed using NIV. Characteristics of patients, context of NIV, and treatment intensity were compared for very old and younger patients. Six-month survival and functional status were assessed in very old patients.
resultsDuring the study period, 1,019 patients needed ventilatory support and 376 (37%) received NIV. Among them, 163 (16%) very old patients received ventilatory support with 60% of them managed using NIV compared with 32% of younger patients (p < 0.0001). Very old patients received NIV more frequently with DNI than in younger patients (40% vs. 8%). Such cases were associated with high mortality for both very old and younger patients. Hospital mortality was higher in very old than in younger patients but did not differ when NIV was used for cardiogenic pulmonary edema or acute-on-chronic respiratory failure (20% vs. 15%) and in postextubation (15% vs. 17%) out of a context of DNI. Six-month mortality was 51% in very old patients, 67% for DNI patients, and 77% in case of NIV failure and endotracheal intubation. Of the 30 hospital survivors, 22 lived at home and 13 remained independent for activities of daily living.
conclusionsVery old patients managed using NIV have an overall satisfactory 6-month survival and functional status, except for endotracheal intubation after NIV failure.
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