Evidence map›Paper›PMID 22353608›Full record

ReviewHypertension (Dallas, Tex. : 1979)2012

Nontraditional roles of angiotensin-converting enzyme.

Xiao Z Shen, Frank S Ong, Ellen A Bernstein, Tea Janjulia, Wendell-Lamar B Blackwell, Kandarp H Shah, Brian L Taylor, Romer A Gonzalez-Villalobos, Sebastien Fuchs, Kenneth E Bernstein

Abstract readReview
In one paragraph

Review in Hypertension (Dallas, Tex. : 1979), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. The absence of intrarenal ACE protects against hypertension.The Journal of clinical investigation · 2013
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xiao Z ShenDepartment of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Frank S Ong
Ellen A Bernstein
Tea Janjulia
Wendell-Lamar B Blackwell
Kandarp H Shah
Brian L Taylor
Romer A Gonzalez-Villalobos
Sebastien Fuchs
Kenneth E Bernstein

Funding

Training Program in Endocrinology, Diabetes, and MetabolismT32DK007770 · NIDDK · CEDARS-SINAI MEDICAL CENTER · PI MELMED, SHLOMO · 1999 to 2022
$3.4M
TESTIS ACE--FUNCTION AND DEVELOPMENTAL EXPRESSIONR01DK051445 · NIDDK · EMORY UNIVERSITY · PI BERNSTEIN, KENNETH E · 1996 to 2008
$2.5M
RAS and InjuryR01HL110353 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI BERNSTEIN, KENNETH E · 2011 to 2015
$2.2M
RENIN/ANGIOTENSIN SYSTEM AND INJURYR01DK039777 · NIDDK · EMORY UNIVERSITY · PI BERNSTEIN, KENNETH E · 1988 to 2010
$1.3M
Importance of the Two Catalytic Sites of ACE in Bleomycin-Induced Lung InjuryR00HL088000 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI FUCHS, SEBASTIEN · 2009 to 2011
$747k
Intrarenal Angiotensin II generation during Angiotensin II-induced hypertensionR00DK083455 · NIDDK · CEDARS-SINAI MEDICAL CENTER · PI GONZALEZ-VILLALOBOS, ROMER ANDRES · 2011 to 2013
$720k
Site-specific ACE Knockout Mice and Bleomycin-Induced Lung InjuryF32HL105036 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI ONG, FRANK SHIH-CHANG · 2011 to 2012
$103k
NHLBI NIH HHS F32 HL105036NHLBI NIH HHS R00 HL088000NHLBI NIH HHS R01 HL110353NIDDK NIH HHS R00-DK051445NIDDK NIH HHS R00 DK083455NIDDK NIH HHS R00DK083455NIDDK NIH HHS R01 DK039777NIDDK NIH HHS R01DK039777NIDDK NIH HHS R01 DK051445NIDDK NIH HHS T32 DK007770NIDDK NIH HHS T32DK007770
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsFertilityHematopoiesisHumansImmune SystemKidneyMaleModels, AnimalNeoplasmsPeptidyl-Dipeptidase ARenin-Angiotensin SystemPeptidyl-Dipeptidase A

Identifiers

PMID22353608
PMCPMC3306543

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.