ArticlePlant physiology2012
Prunasin hydrolases during fruit development in sweet and bitter almonds.
Article in Plant physiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Aberrant glycosylation in hematologic malignancies: mechanisms, immune evasion, and therapeutic targeting.Blood cancer journal · 2026Review
- Graft compatibility emerges from the balance between regeneration and immunity: lessons from plant-plant interactions.Frontiers in plant science · 2026Review
- Antifeedant activity of invasive Prunus serotina leaves methanolic extract against Sitophilus granarius, a pest of stored products.Scientific reports · 2025Article
- Mandelonitrile lyase MDL2-mediated regulation of seed amygdalin and oil accumulation of Prunus Sibirica.BMC plant biology · 2024Article
- Transcriptome analysis reveals genes associated with the bitter-sweet trait of apricot kernels.Forestry research · 2024Article
- Exploring the wild almond,Tree genetics & genomes · 2024Article
- A review on some properties of almond: ımpact of processing, fatty acids, polyphenols, nutrients, bioactive properties, and health aspects.Journal of food science and technology · 2023Review
- Accumulation Pattern of Amygdalin and Prunasin and Its Correlation with Fruit and Kernel Agronomic Characteristics during Apricot (Foods (Basel, Switzerland) · 2021Article
- Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Imaging of Metabolites during Sorghum Germination.Plant physiology · 2020Article
- Dynamic metabolic solutions to the sessile life style of plants.Natural product reports · 2018Review
- Elucidation of the Amygdalin Pathway Reveals the Metabolic Basis of Bitter and Sweet Almonds (Plant physiology · 2018Article
- Article
- The Intracellular Localization of the Vanillin Biosynthetic Machinery in Pods of Vanilla planifolia.Plant & cell physiology · 2018Article
- Dual role of imidazole as activator/inhibitor of sweet almond (Biochemistry and biophysics reports · 2017Article
- Cyanogenic Glucosides and Derivatives in Almond and Sweet Cherry Flower Buds from Dormancy to Flowering.Frontiers in plant science · 2017Article
- Seasonal Changes Affect Root Prunasin Concentration in Prunus serotina and Override Species Interactions between P. serotina and Quercus petraea.Journal of chemical ecology · 2016Article
- Nutritional value and volatile compounds of black cherry (Prunus serotina) seeds.Molecules (Basel, Switzerland) · 2015Article
- The multicopy sRNA LhrC controls expression of the oligopeptide-binding protein OppA in Listeria monocytogenes.RNA biology · 2015Article
- Comparative genomics analysis in Prunoideae to identify biologically relevant polymorphisms.Plant biotechnology journal · 2013Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Amygdalin is a cyanogenic diglucoside and constitutes the bitter component in bitter almond (Prunus dulcis). Amygdalin concentration increases in the course of fruit formation. The monoglucoside prunasin is the precursor of amygdalin. Prunasin may be degraded to hydrogen cyanide, glucose, and benzaldehyde by the action of the β-glucosidase prunasin hydrolase (PH) and mandelonitirile lyase or be glucosylated to form amygdalin. The tissue and cellular localization of PHs was determined during fruit development in two sweet and two bitter almond cultivars using a specific antibody toward PHs. Confocal studies on sections of tegument, nucellus, endosperm, and embryo showed that the localization of the PH proteins is dependent on the stage of fruit development, shifting between apoplast and symplast in opposite patterns in sweet and bitter cultivars. Two different PH genes, Ph691 and Ph692, have been identified in a sweet and a bitter almond cultivar. Both cDNAs are 86% identical on the nucleotide level, and their encoded proteins are 79% identical to each other. In addition, Ph691 and Ph692 display 92% and 86% nucleotide identity to Ph1 from black cherry (Prunus serotina). Both proteins were predicted to contain an amino-terminal signal peptide, with the size of 26 amino acid residues for PH691 and 22 residues for PH692. The PH activity and the localization of the respective proteins in vivo differ between cultivars. This implies that there might be different concentrations of prunasin available in the seed for amygdalin synthesis and that these differences may determine whether the mature almond develops into bitter or sweet.
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